Thioamidoalkylation of 1,3-Dicarbonyl Compounds, Enol Silyl Ethers, and Enamines

Alan R. Katritzky; Ilhami Celik; Ashraf A. A. Abdel-Fattah

doi:10.1055/s-2007-966064

PAPER

Thioamidoalkylation of 1,3-Dicarbonyl Compounds, Enol Silyl Ethers, and Enamines

Alan R. Katritzky*^a, Ilhami Celik^a,b, Ashraf A. A. Abdel-Fattah^a,c
^a Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, FL 32611-7200, USA
Fax: +1(352)3929199; e-Mail: katritzky@chem.ufl.edu.;
^b Department of Chemistry, Faculty of Science, Anadolu University, 26470 Eskisehir, Turkey
^c Department of Chemistry, Faculty of Science, Benha University, Benha, Egypt

Abstract

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Abstract

Novel syntheses of β-thioamido ketones via thioamidoalkylations of malonates, β-keto esters, β-diketones, enol silyl ethers, and enamines with N-(α-thioamidoalkyl)benzotriazoles are described.

Key words

thioamides - N-(α-thioamidoalkyl)benzotriazoles - thioamidoalkylation - 1,3-dicarbonyl compounds - enol silyl ethers - enamines

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References

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