Radiologie up2date 2007; 7(2): 115-132
DOI: 10.1055/s-2007-966523
Pulmonale und kardiovaskuläre Radiologie

© Georg Thieme Verlag KG Stuttgart · New York

Pulmonale Manifestationen bei systemischen Vaskulitiden

Pulmonary manifestations from systemic vasculitidesM.  Reuter, M.  Both, A.  Schnabel
Further Information

Publication History

Publication Date:
14 June 2007 (online)

Zusammenfassung

Die pulmonalen Vaskulitiden sind Kleingefäßvaskulitiden und umfassen neben der Wegener-Granulomatose die mikroskopische Polyangiitis und das Churg-Strauss-Syndrom. Die Takayasu-Arteriitis als Großgefäßvaskulitis führt zu Stenosen an den Pulmonalarterien.
Für die Interpretation der radiologischen Befunde sind Kenntnisse des oft mehrphasigen Krankheitsverlaufes und des klinischen Erscheinungsbildes der Lungenmanifestationen hilfreich. Daher vermittelt dieser Artikel neben den radiologischen Befunden im Übersichtsbild und im hochauflösenden CT auch klinische Aspekte der pulmonalen Vaskulitiden. Neben der Bestimmung der Krankheitsausdehnung steht die Festlegung der Krankheitsaktivität im Vordergrund der bildgebenden Diagnostik. In diesem Zusammenhang wird auch auf die Therapieprinzipien eingegangen.

Abstract

Pulmonary vasculitides predominantly involve the small arterioles, capillaries and venules and include Wegener's granulomatosis, microscopic polyangiitis and the Churg-Strauss syndrome. Takayasu's arteriitis is a large vessel disease and may affect the main pulmonary arteries causing stenoses and occlusions.

Knowledge of the natural course of disease and of clinical manifestations of pulmonary disease is helpful for an understanding of imaging findings. For this reason this article gives an overview not only of radiologic findings in chest X-ray and high resolution CT of the lungs but as well of clinical aspects of pulmonary vasculitides. Next to determination of disease extension the determination of disease activity is in the foreground of diagnostic imaging in vasculitides. Within this context principals of immunosuppressive therapy will be recognized.

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Prof. Dr. Michael Reuter

Institut für Radiologie und Interventionelle Therapie

Vivantes Klinikum Neukölln

Rudower Str. 48

12351 Berlin

Phone: 030/6004-2070

Fax: 030/6004-3271

Email: michael.reuter@vivantes.de