Subscribe to RSS
DOI: 10.1055/s-2007-966977
© Georg Thieme Verlag KG Stuttgart · New York
Stellenwert der Blutabnahme vor Adenotomie
Significance of Blood Tests Prior to AdenoidectomyPublication History
eingereicht 16. März 2007
akzeptiert 10. September 2007
Publication Date:
25 October 2007 (online)
Zusammenfassung
Hintergrund: Die gemeinsame Stellungnahme der Gesellschaften für Hals-Nasen- und Ohrenheilkunde, Pädiatrie sowie Anästhesie zur Notwendigkeit präoperativer Gerinnungsdiagnostik vor Adenotomien und Tonsillektomien bei Kindern veranlasste uns, eine retrospektive Analyse unseres Patientengutes durchzuführen.
Methode und Patienten: Retrospektiv wurden Daten von 1137 Patienten analysiert, die in 2005 und 2006 in unserer Klinik eine Adenotomie erhalten hatten. Neben dem Geschlecht, Alter, Hb, Thrombozytenzahl, Quick, INR, PTT, TZ wurde auch der klinische Verlauf erfasst.
Ergebnisse: Pathologische Werte fanden sich in 3 % aller Laboruntersuchungen, aber nur 0,12 % der Parameter hatten als Konsequenz, dass keine Operation stattfand. Aufgrund auffälliger Laborparameter erfolgte somit in 7 Fällen kein Eingriff. Hierbei handelte es sich in je drei Fällen um eine Thrombozytopenie (< 100 000 Zellen/µl) sowie um eine Anämie (Hb < 10 g/dl) und in einem Fall um eine PTT-Verlängerung. Drei dieser Patienten konnten zu einem späteren Zeitpunkt operiert werden. Insgesamt wurden 11 AT-Nachblutungen beobachtet und z. T. operativ (6) versorgt. Bei diesen 11 Patienten mit AT-Nachblutungen lagen die Thrombozytenzahlen und die anderen bestimmten Gerinnungsparameter im Normbereich.
Schlussfolgerungen: Aufgrund der hier vorgestellten Daten und der aktuellen Literatur ist eine Blutanalysen nur bei Patienten mit einer auffälligen Blutungsanamnese oder Anämie oder einer auffälligen Familienanamnese erforderlich. Die standardisierte präoperative Dokumentation der Blutungsanamnese in den Krankenunterlagen wird dringend empfohlen.
Abstract
Background: Hörmann recently published a joint statement of the German Societies of Oto-Rhino-Laryngology, Head and Neck surgery, of pediatrics and of anesthesiology regarding the necessity of coagulation tests prior to adenoidectomy or tonsillectomy in children. According to many studies, these societies agreed that coagulation tests should be performed only in children with an unusual bleeding history. We analyzed our adenoidectomy-database to investigate the need for preoperative blood tests to prevent bleeding events during and following an adenoidectomy. Methods and Patients: Data of 1137 children were collected, undergoing adenoidectomy during a period of 18 months (2005/2006) at the Bochum department of Oto-Rhino-Laryngology, retrospectively. Information on sex, age, hemoglobin concentration, platelet count, INR, thromboplastin time and prothrombin time and clinical bleeding history were collected. Results: 3 % of the laboratory investigations showed pathological parameters. Only 0.12 % of the tests resulted in the cancellation of the operation (7 cases). The reasons for cancellation were: platelet count less than 100 000/µl (3 patients), anemia (Hb < 10 g/dl) (3 patients) and prolongated thromboplastin time (1 patient). 3 of these 7 patients were operated later on. Postoperative hemorrhage was noticed in 11 patients following adenoidectomy. In these 11 patients with bleeding complications all laboratory parameters were found to be normal. Conclusions: In accordance with the current literature our data show that bleeding after adenoidectomy is a rare complication. In contrast to many other studies, we also report weak bleedings from the epipharynx. Blood tests were routinely performed prior to every operation with little benefit. Only 4 patients were definitely not scheduled for surgery as a consequence of the preoperative blood test. Patients with bleeding complications were not suspicious regarding laboratory workup. We therefore conclude that blood tests prior to adenoidectomy have no relevance for the course of the operation and postoperative bleeding event. Blood tests should only be performed on patients with an unusual bleeding history, family bleeding history or indications for anemia. The documentation of a standardized bleeding history prior to surgery is strongly recommended.
Schlüsselwörter
Adenotomie - präoperative Blutabnahme - Gerinnungsdiagnostik - Inzidenz von Nachblutungen - operatives Management von Nachblutungen aus dem Epipahyrnx - Anamnesebogen zur Blutungsneigung
Key words
adenoidectomy - preoperative blood tests - coagulation tests - incidence of bleedings - operative management of bleedings from the epipharynx
Literatur
- 1 Pratt L W, Gallagher R A. Tonsillectomy and adenoidectomy: Incidence and Maortality, 1968 - 1972. Otolaryngol Head and Neck Surg. 1979; 87 59-166
- 2 Jimenez-Yuste V, Prim M P, De Diego J I, Villar A, Quintana M, Rabanal I, Sastre N, Hernandez-Navarro F. Otolaryngologic surgery in children with von Willebrand disease. Arch Otolaryngol Head Neck Surg. 2002; 128 1365-1368
- 3 Hörmann K. Gemeinsame Stellungnahme zur Notwendigkeit präoperativer Gerinnungsdiagnostik vor Tonsillektomie und Adenotomie bei Kindern. Laryngo-Rhino-Otol. 2006; 85 580-581
- 4 Eberl W, Wendt I, Schroeder H G. Präoperatives Screening auf Gerinnungsstörungen vor Adenotomie und Tonsillektomie. Klin Pädiatr. 2005; 217 20-24
- 5 Alexandria V A. The American Academy of Otolaryngology-Head and Neck Surgery. Clinical Indicators Compendium 1999
- 6 Manning S C, Beste D, McBride T, Goldberg A. An assessment of preoperative coagulation screening for tonsillectomy and adenoidectomy. Int J Pediatr Otorhinolaryngol. 1987; 13 237-244
- 7 Roy W L, Lerman J, McIntyre B G. Is preoperative haemoglobin testing justified in children undergoing minor elective surgery?. Can J Anaesth. 1991; 38 700-703
- 8 Hoare T J. Pre-operative haemoglobin estimation in paediatric ENT surgery. J Laryngol Otol. 1994; 108 920-921
- 9 Zwack G C, Derkay C S. The utility of preoperative hemostatic assessment in adenotonsillectomy. Int J Pediatr Otorhinolaryngol. 1997; 39 67-76
- 10 Chee Y L, Greaves M. Role of coagulation testing in predicting bleeding risk. Hematol J.. 2003; 4 373-378
- 11 Gabriel P, Mazoit X, Ecoffey C. Relationship between clinical history, coagulation tests, and perioperative bleeding during tonsillectomies in pediatrics. J Clin Anesth. 2000; 12 288-291
- 12 Kang J, Brodsky L, Danziger I, Volk M, Stanievich J. Coagulation profile as a predictor for post-tonsillectomy and adenoidectomy (T + A) hemorrhage. Int J Pediatr Otorhinolaryngol. 1994; 28 157-165
- 13 Mutz I, Simon H. Hemorrhagic complications after tonsillectomy and adenoidectomy. Experiences with 7743 operations in 14 years. Wien Klin Wochenschr. 1993; 105 520-522
- 14 Windfuhr J P, Chen Y S, Remmert S. Hemorrhage following tonsillectomy and adenoidectomy in 15 218 patients. Otolaryngol Head Neck Surg. 2005; 132 281-286
- 15 Dib G C, Kosugi E M, Neto J M, Antunes M L, Morales D SR, Guilherme A, Fujuda Y. Postoperative hemorrhage in 397 adenotonsillectomies performed at hospital Geral de Pirajussara (HGP) and Hospital Estdual de Diadema (HED)/Federal University of Sao Paulo (UNIFESP-EPM). Rev Bras Otorinolaringol. 2004; 70
- 16 Capper J WR, Randall C. Post operative haemorrhage in tonsillectomy and adenoidectomy in children. J Laryngol Otol. 1984; 98 363-365
- 17 Asaf T, Reuveni H, Yermiahu T, Leiberman A, Gurman G, Porat A, Schlaeffer P, Shifra S, Kapelushnik J. The need for routine pre-operative coagulation screening tests (prothrombin time PT/partial thromboplastin time PTT) for healthy children undergoing elective tonsillectomy and/or adenoidectomy. Int J Pediatr Otorhinolaryngol. 2001; 61 217-222
- 18 Perry J J, Alving B M. Von Willebrand’s disease. Am Fam Physician. 1990; 41 219-224
- 19 Rapaport S. Preoperative hemostatic evaluation: Which tests, if any?. Blood. 1983; 61 229-231
- 20 Fritsche P. Adeno-Tonsillektomie-Nachblutungen aus der Sicht des Anaesthesisten. HNO. 1981; 29 397-400
- 21 Crysdale W S, Russel D. Complications of tonsillectomy and adenoidectomy in 9409 children observed overnight. CMAJ. 1986; 135 1139-1142
- 22 Kubo I. Über die Nachblutungen nach Adenotomie. European Archives of Oto-Rhino-Laryngology. Berlin, Heidelberg; Springer 1931: 201-207
- 23 Wustrow T P. Wie ich es mache - Wie beuge ich einer stärkeren Blutung bei der Adenotomie vor?. Laryngo-Rhino-Otologie. 1989; 68 304-305
- 24 Jimenez-Yuste V, Prim M P, De Diego J I, Villar A, Quintana M, Rabanal I, Sastre N, Hernandez-Navarro F. Otolaryngologic surgery in children with von Willebrand disease. Arch Otolaryngol Head Neck Surg. 2002; 128 1365-1368
- 25 Schwab M, Ruder H. Hponatremia and cerebral convulsion due to DDAVP administration in patients with enuresis nocturna or urine concentration testing. Eur J Pediatr. 1997; 156 668
-
26 Rettinger G.
Eingriffe am Epipharynx. Adenotomie. In: Theissing J (Hrsg). HNO-Operationslehre. 3. Auflage. Stuttgart; Thieme 1996: 163 - 27 Paqueron X, Favier R, Richard P, Maillet J, Murat I. Severe postadenoidectomy bleeding revealing congenital alpha 2 antiplasmin deficiency in a child. Anesth Analg. 1997; 84 1147-1149
- 28 Burk C D, Miller L, Handler S D, Chen A R. Preoperative history and coagulation screening in children undergoing tonsillectomy. Padiatrics. 1992; 89 691-695
- 29 Tami T A, Parker G S, Taylor R E. Post-tonsillectomy bleeding; an evaluation of risk factors. Laryngoscope. 1987; 97 1307-1311
- 30 Close H L, Kryzer T C, Nowlin J H. Hemo-staticassessment of patients before tonsillectomy: a prospective study. Otolaryngol Head Neck Surg. 1994; 111 733-738
- 31 Krishna P, Lee D. Post-tonsillectomy bleeding: a meta-analysis. Laryngoscope. 2001; 111 1358-1361
- 32 The Swedish Council on Technology Assessment in Health Care . Preoperative routines. Int J Tech Assess Health Care. 1991; 7 95-100
- 33 Prim M P, De Diego J I, Jimenez-Yuste V, Sastre N, Rabanal I, Gavilan J. Analysis of the causes of immediate unanticipated bleeding after pediatric adenotonsillectomy. Int J Pediatr Otorhinolaryngol.. 2003; 67 341-344
- 34 Garcia Callejo F J, Pardo Mateu L, Velert Vila M M, Orts Alborch M, Monzo Gandia R, Marco Algarra J. Usefulness of preoperative coagulation tests in the prevention of post-tonsillectomy hemorrhage in children. Acta Otorrinolaringol Esp. 1997; 48 473-478
- 35 Ferrante F, Fattorini L, Bifarini B, Tesoro S. Coagulation Screening for Otorhinolaryngoiatric Surgery: A Pharmacoeconomic Appraisal in the Setting of the Italian National Health System. Journal of Thrombosis and Haemostasis. 2005; 3 (Suppl. 1) Abstract Number PO 249
- 36 Onakoya P A, Nwaorgu O GB, Abja U M, Kokong D D. Adenoidectomy and tonsillectomy: is clotting profile relevant?. Nigerian Journal of Surgical Research. 2004; 6 34-36
- 37 Shamboul K, Yousif Y M. Tonsillectomy and adenotonsillectomy in Sudanese patients. East Afr Med J. 2001; 78 405-407
- 38 Windfuhr J P, Hübner R, Sesterhenn K. Kriterien zur stationären Krankenhausbehandlung der Adenotomie. HNO. 2003; 51 622-628
- 39 Peeters A, Van Rompaey D, Schmelzer B, Vidts G, Katz S. Tonsillectomy and adenotomy as a one day procedure?. Acta Otorhinolaryngol Belg. 1999; 53 91-97
- 40 Wei J L, Beatty C W, Gustafson R O. Evaluation of posttonsillectomy hemorrhage and risk factors. Otolaryngol Head Neck Surg. 2000; 123 229-235
- 41 Richmond K H, Wetmore R F, Baranak C C. Postoperative complications following tonsillectomy and adenoidectomy - who is at risk?. Int J Pediatr Otorhinolaryngol. 1987; 13 117-124
- 42 Mills N, Anderson B J, Barber C, White J, Mahadevan M, Salkeld L, Douglas G, Brown C. Day stay pediatric tonsillectomy - a safe procedure. Int J Pediatr Otorhinolaryngol. 2004; 68 1367-1373
- 43 Chee N W, Chan K O. Clinical audit on tonsils and adenoid surgery. Is day surgery a reasonable option?. Ann Acad Med Singapore. 1996; 25 245-250
Dr. med. Matthias Schwaab
Klinik für HNO-Heilkunde, Kopf- und Halschirurgie der Ruhr-Universität Bochum,
St. Elisabeth-Hospital
Bleichstraße 15
44787 Bochum
Email: matthiasschwaab@gmx.de