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Planta Med 2007; 73(2): 187-189
DOI: 10.1055/s-2007-967103
Letter
© Georg Thieme Verlag KG Stuttgart · New York

Pycnanthuquinone C: A New Terpenoid-Quinone from Pycnanthus angolensis

Hippolyte K. Wabo1 , Simplice N. Tatsimo2 , Pierre Tane1 , Joseph D. Connolly3
  • 1Department of Chemistry, University of Dschang, Dschang, Cameroon
  • 2Department of Organic Chemistry, University of Yaounde I, Yaounde, Cameroon
  • 3Chemistry Department, University of Glasgow, Glasgow, Scotland, U.K.
Further Information

Publication History

Received: July 10, 2006

Accepted: December 11, 2006

Publication Date:
13 February 2007 (online)

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Abstract

A new compound containing a unique terpenoid-quinone skeleton, pycnanthuquinone C (1) along with the known sargachromenol (2), prunetin (3), biochanin A (4), calopiptin (5), (12S,13S)-12,13-dihydroxylabda-8(17),14-dien-18-oic acid (6), (12R,13S)-12,13-dihydroxylabda-8(17),14-dien-18-oic acid (7), and sitosterol 3-O-β-D-glucopyranoside (8), were isolated from the stem bark of Pycnanthus angolensis. Their structures were elucidated by spectroscopic means and comparison with published data. The antifungal activity of compounds 1, 2 and 3 was evaluated. Compound 1 was active against Trichophyton soudanense. Compound 2 was active against Trichophyton mentagrophytes while compound 3 was active against Microsporum audouinii and Trichophyton mentagrophytes.

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Prof. Pierre Tane

Department of Chemistry

University of Dschang

P.O. Box 67

Dschang

Cameroon

Phone: +237-761-95-46

Fax: +237-345-17-35

Email: ptane@yahoo.com