ABSTRACT
Recent surveys have indicated that thromboembolic complications are at least as common
in hematologic malignancies, if not more frequent, than in solid tumors. The pathogenesis
of thrombosis is similar to that in solid tumors, but with additional factors unique
in several forms of hematologic malignancies, as seen in acute promyelocytic leukemia,
myeloma, and myeloproliferative disorders. Likewise, the factors contributing to bleeding
are similar to those seen in solid tumors, with the exception of a higher frequency
of thrombocytopenia.
KEYWORDS
Leukemia - lymphoma - procoagulants - thrombosis - bleeding
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Hau C KwaanM.D.
Division of Hematology/Oncology, Feinberg School of Medicine, Northwestern University
303 East Chicago Ave., Chicago, IL 60611
eMail: h-kwaan@northwestern.edu
