Introduction
<P>Oxalyl chloride is a very versatile reagent extensively used by organic chemists.
One of its most common uses is in oxidation of alcohols to aldehydes and ketones named
Swern oxidation.
[
1-5]
However, this reagent can efficiently be applied in many other reactions such as 1,1-cycloadditions
with 1,4-dilithio-1,3-dienes or zirconacyclopentadienes,
[
6]
cyclization of 1,3-bis(trimethylsilyloxy) alk-1-enes to isoeletronic acids,
[
7]
preparation of phenyl isocyanates from anilines,
[
8]
bicyclization of biaryl acetamides,
[
9]
dehydration of formamides to afford nitriles,
[
10]
and cyclization of 1,1-bis(trimethylsilyloxy) ketene acetals to give 3-hydroxymaleic
anhydrides.
[
11]
</P>
