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Planta Med 2007; 73(11): 1195-1196
DOI: 10.1055/s-2007-981582
Pharmacology
Letter
© Georg Thieme Verlag KG Stuttgart · New York

Mangiferin Identified in a Screening Study Guided by Neuraminidase Inhibitory Activity

Xiaofan Li1 , Takashi Ohtsuki1 , Sayaka Shindo1 , Masaaki Sato1 , Takashi Koyano2 , Srisomporn Preeprame3 , Thaworn Kowithayakorn4 , Masami Ishibashi1
  • 1Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan
  • 2Temko Corporation, Tokyo, Japan
  • 3Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen, Thailand
  • 4Faculty of Agriculture, Khon Kaen University, Khon Kaen, Thailand
Further Information

Publication History

Received: April 5, 2007 Revised: June 30, 2007

Accepted: July 2, 2007

Publication Date:
23 August 2007 (online)

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Abstract

A screening study on neuraminidase inhibitory constituents was carried out, and activity-guided fractionations of three plants, Gouania obtusifolia, Zizyphus cambodiana, and Mangifera odorata, led to the isolation of eleven compounds (1 - 11). Mangiferin was identified as a significant neuraminidase inhibitor.

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Prof. Masami Ishibashi

Graduate School of Pharmaceutical Sciences

Chiba University

1-33 Yayoi-cho

Inage-ku,

Chiba 263-8522

Japan

Phone: +81-43-290-2913

Fax: +81-43-290-2913

Email: mish@p.chiba-u.ac.jp

    www.thieme-connect.de/ejournals/toc/plantamedica