Abstract
The hemiprotected diols 7 and 8 , which are prospective precursors of carbanucleosides of this family, were prepared from the mesylates of the corresponding higher homologues by elimination of the mesyloxy group using 1,8-diazabicyclo[5.4.0]undec-7-ene followed by ozonolysis and reduction of the ozonide with sodium borohydride.
Key words
cyclopenta[d ]pyridazines - silyl ethers - diols - ozonolysis - Mitsunobu reaction
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10 The crystallographic data of cis -7 have been deposited with the Cambridge Crystallographic Data Centre (CCDC) with number 630734. Empirical formula: C26 H32 N2 O2 Si; formula weight: 432.63; crystal size: 0.51 × 0.33 × 0.06; crystal colour, habit: colourless, prismatic; crystal system: monoclinic; lattice type: plate; lattice parameters: a = 6.309 (5) Å, b = 12.889 (5) Å, c = 15.172 (5) Å, α = 90 (5)°, β = 96.818 (5)°, γ = 90 (5)°, V = 1225 0(12) Å3 ; space group: P 21 ; Z = 2; D
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