Preparation of a C ₂-Symmetric Binol-Derived Diol and Its Application in the Catalytic Enantioselective and Catalyst-Controlled Diastereoselective Allylboration of Aldehydes

Abstract

A novel C ₂-symmetric Binol-derived diol is described. It is readily applicable towards combined acid catalysis for the asym­metric allylboration of aldehydes to provide homoallylic alcohols in high enantioselectivities, and dictates the diastereoselectivity in the reaction of an achiral allylboronate with chiral aldehydes.

Keywords

allylboration - Brønsted acid - enantioselective catalysis - chiral diol - propionate units

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