Noncontiguous Bilateral Esthesioneuroblastoma: A Case Report

Annesse Lee; David P. Goldstein; Jonathan Irish; Fred Gentili; Bayardo Perez-Ordonez

doi:10.1055/s-2007-986459

Skull Base, Table of Contents

Skull Base 2007; 17(6): 405-407
DOI: 10.1055/s-2007-986459

CASE REPORT

Noncontiguous Bilateral Esthesioneuroblastoma: A Case Report

Annesse Lee¹ , David P. Goldstein² , Jonathan Irish³ , Fred Gentili⁴ , Bayardo Perez-Ordonez⁵

¹Division of Otolaryngology-Head and Neck Surgery, McMaster University, Hamilton, Ontario, Canada
²Department of Otolaryngology-Head and Neck Surgery, University Health Network, University of Toronto, Toronto, Ontario, Canada
³Department of Surgical Oncology, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada
⁴Division of Neurosurgery, University Health Network, University of Toronto, Toronto, Ontario, Canada
⁵Department of Pathology, University Health Network, University of Toronto, Toronto, Ontario, Canada

Abstract

ABSTRACT

Esthesioneuroblastoma is a rare malignant neoplasm arising from the olfactory epithelium. This tumor has a tendency to originate from one side of the nasal cavity or paranasal sinuses with frequent extension into the contralateral nasal cavity through direct invasion. A review of the literature reveals numerous case reports describing esthesioneuroblastoma with unilateral or bilateral involvement; however, there have been no known reports of bilateral noncontiguous (multifocal) esthesioneuroblastoma. We present a unique case of a patient diagnosed with two separate primary esthesioneuroblastomas who was managed with preoperative radiation followed by surgical resection of the tumor. This case illustrates that esthesioneuroblastoma must remain as part of the differential diagnosis for a multifocal, noncontiguous intranasal and paranasal sinus mass.

KEYWORDS

Esthesioneuroblastoma - noncontiguous sinus mass - olfactory neuroblastoma

Full Text

References

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Annesse LeeM.D.

Division of Otolaryngology-Head and Neck Surgery, McMaster University

3V1-1200 Main Street West, Hamilton, Ontario, Canada L8N 3Z5

Email: Annesse.Lee@learnlink.mcmaster.ca