Subscribe to RSS
DOI: 10.1055/s-2007-989340
© Georg Thieme Verlag KG Stuttgart · New York
Surgical Outcome of Inflammatory Pseudotumor in the Lung
Publication History
received July 24, 2007
Publication Date:
15 May 2008 (online)
![](https://www.thieme-connect.de/media/thoracic/200804/lookinside/thumbnails/10.1055-s-2007-989340-1.jpg)
Abstract
Background: Pulmonary inflammatory pseudotumors are rare, and little is known about their clinical behavior and surgical outcome. Materials and Methods: Between 1993 and 2003, 19 patients with inflammatory pseudotumor were managed in our hospital. We retrospectively reviewed the clinical and radiographic features, as well as the surgical outcomes. Results: Of the 19 patients (15 men, 4 women; mean age 53.9 years), 6 underwent lobectomy, 11 had wedge resections, and 2 had biopsy alone. There was no recurrence of the lesion in the 17 patients who underwent resection or lobectomy of the pseudotumor. There was no disease progression in the 2 patients who had only had a biopsy. Conclusion: Inflammatory pseudotumor of the lung is relatively benign. Complete resection leads to an excellent outcome.
Key words
thoracic surgery - lung tumor - prognosis
References
- 1 Mitsudomi T, Kaneko S, Tateishi M. et al . Benign tumors and tumor-like lesions of the lung. Int Surg. 1990; 75 155-158
- 2 Cerfolio R J, Allen M S, Nascimento A G. et al . Inflammatory pseudotumors of the lung. Ann Thorac Surg. 1999; 67 933-936
- 3 Melloni G, Carretta A, Ciriaco P. et al . Inflammatory pseudotumor of the lung in adults. Ann Thorac Surg. 2005; 79 426-432
- 4 Sakurai H, Hasegawa T, Watanabe S. et al . Inflammatory myofibroblastic tumor of the lung. Eur J Cardiothorac Surg. 2004; 25 155-159
- 5 Pettinato G, Manivel J C, De Rosa N, Dehner L P. Inflammatory myofibroblastic tumor (plasma cell granuloma). Clinicopathologic study of 20 cases with immunohistochemical and ultrastructural observations. Am J Clin Pathol. 1990; 94 538-546
- 6 Berman M, Georghiou G P, Schonfeld T. et al . Pulmonary inflammatory myofibroblastic tumor invading the left atrium. Ann Thorac Surg. 2003; 76 601-603
- 7 Lawrence B, Perez-Atayde A, Hibbard M K. et al . TPM3-ALK and TPM4-ALK oncogenes in inflammatory myofibroblastic tumors. Am J Pathol. 2000; 157 377-384
- 8 Gomez-Roman J J, Sanchez-Velasco P, Ocejo-Vinyals G. et al . Human herpesvirus-8 genes are expressed in pulmonary inflammatory myofibroblastic tumor (inflammatory pseudotumor). Am J Surg Pathol. 2001; 25 624-629
- 9 Berardi R S, Lee S S, Chen H P, Stines G J. Inflammatory pseudotumors of the lung. Surg Gynecol Obstet. 1983; 156 89-96
- 10 Agrons G A, Rosado-de-Christenson M L, Kirejczyk W M. et al . Pulmonary inflammatory pseudotumor: radiologic features. Radiology. 1998; 206 511-518
- 11 Bahadori M, Liebow A A. Plasma cell granulomas of the lung. Cancer. 1973; 31 191-208
- 12 Copin M C, Gosselin B H, Ribet M E. Plasma cell granuloma of the lung: difficulties in diagnosis and prognosis. Ann Thorac Surg. 1996; 61 1477-1482
- 13 Matsubara O, Tan-Liu N S, Kenney R M, Mark E J. Inflammatory pseudotumors of the lung: progression from organizing pneumonia to fibrous histiocytoma or to plasma cell granuloma in 32 cases. Hum Pathol. 1988; 19 807-814
-
14 Coffin C M, Fletcher J A.
Inflammatory myofibroblastic tumor. Fletcher CDM, Unni KK, Mertens F World Health Organization Classification of Tumors: Pathology and Genetics, Tumors of Soft Tissue and Bone. Lyon; IARC Press 2002: 91-93 - 15 Gal A A, Koss M N, McCarthy W F, Hochholzer L. Prognostic factors in pulmonary fibrohistiocytic lesions. Cancer. 1994; 73 1817-1824
- 16 Urschel J D, Horan T A, Unruh H W. Plasma cell granuloma of the lung. J Thorac Cardiovasc Surg. 1992; 104 870-875
- 17 Colakoglu O, Unsal B, Haciyanli M. et al . A successfully managed inflammatory pseudotumour of liver without surgery: report of a case. Acta Gastroenterol Belg. 2005; 68 382-384
Dr. MD Chih-Hao Chen
Department of Thoracic Surgery
Mackay Memorial Hospital
92, Section 2, Chungshan North Road
10449 Taipei City
Taiwan - Republic of China
Phone: + 886 2 25 43 35 35
Fax: + 886 2 25 43 36 42
Email: musclenet2003@yahoo.com.tw