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DOI: 10.1055/s-2007-990235
© Georg Thieme Verlag KG Stuttgart · New York
Bioactive Phenols from the Leaves of Baccaurea ramiflora
Publication History
Received: May 28, 2007
Revised: August 22, 2007
Accepted: September 5, 2007
Publication Date:
04 October 2007 (online)
![](https://www.thieme-connect.de/media/plantamedica/200713/lookinside/thumbnails/10.1055-s-2007-990235-1.jpg)
Abstract
Two new phenols, 6′-O-vanilloylisotachioside (1) and 6′-O-vanilloyltachioside (2), together with nine known compounds, were isolated from the leaves of Baccaurea ramiflora (Euphorbiaceae). The structures of the new compounds were elucidated mainly by analysis of physical and spectroscopic data. Compounds 1 - 10 were tested for antioxidant activities by using MTT and DPPH assays. Seven compounds, 1, 2, and 4 - 8, revealed potent antioxidant activities against H2O2-induced impairment in PC12 cells, and exhibited significant DPPH radical-scavenging activities with IC50 values of 86.9, 142.9, 15.2, 37.6, 35.9, 30.2, and 79.8 μM, respectively.
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Prof. Dr. Xiao-Jiang Hao
Key Laboratory of Phytochemistry and Plant Resources in West China
Kunming Institute of Botany
Chinese Academy of Sciences
Kunming 650204
People’s Republic of China
Phone: +86-871-522-3263
Fax: +86-871-521-9684
Email: haoxj@mail.kib.ac.cn
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