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Design for Morphine Alkaloids by Intramolecular Heck Strategy: Chemoenzymatic Synthesis of 10-Hydroxy-14-epi-dihydrocodeinone via C-D-B Ring Construction

Josef Zezulaa, Kenner C. Ricea, Tomas Hudlicky*b
a Drug Design and Synthesis Section, Chemical Biology Research Branch, Building 8, Room B1-23, , National Institute of Drug Abuse, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, 20892-0815, USA
b Department of Chemistry and Centre for Biotechnology, Brock University, 500 Glenridge Ave, St. Catharines, ON, L2S 3A1, Canada
Fax: +1(905)9844841; e-Mail: thudlicky@brocku.ca;