Am J Perinatol 1998; 15(11): 597-600
DOI: 10.1055/s-2007-994076
ORIGINAL ARTICLE

© 1998 by Thieme Medical Publishers, Inc.

Fatal Maternal β-Hemolytic Group B Streptococcal Meningitis: A Case Report

Roy R. Wolfe1, Jr.2 , Monica L. Norwick1 , 2 , James A. Bofill2
  • 1Department of Obstetrics and Gynecology, Wright-Patterson USAF Medical Center, WPAFB, Ohio
  • 2Department of Obstetrics and Gynecology, Wright State University School of Medicine, Dayton, Ohio
Further Information

Publication History

Publication Date:
04 March 2008 (online)

ABSTRACT

Meningitis secondary to β-hemolytic group B streptococcus is rare and represents less than 1% of cases of adult meningitis. We report the first known case of maternal mortality attributed to β-hemolytic group B streptococcal meningitis. A 23-year-old African-American woman with a benign prenatal course delivered a viable male infant at term. Labor was complicated by thick meconium for which a saline amnioinfusion was utilized. On postpartum Day 1, the patient complained of right hip pain and a headache. Within 12 hr the patient was comatose with fixed and dilated pupils. Life support measures were discontinued secondary to absence of electrocortical activity. Postmortem examination revealed endomyometritis and fulminant meningitis with gram-positive cocci. Placental histologic sections demonstrated acute chorioamnionitis and bateriological cultures noted β-hemolytic group B streptococcus. The virulence of β-hemolytic group B streptococcus in the neonate is well recognized. This case demonstrates that β-hemolytic group B streptococcus is also a potentially fatal maternal pathogen.