Coagulation Studies in Patients with Marked Thrombocytopenia due to Severe Preeclampsia

Jose A. Prieto; Joan M. Mastrobattista; Jorge D. Blanco

doi:10.1055/s-2007-994457

American Journal of Perinatology, Table of Contents

Am J Perinatol 1995; 12(3): 220-222
DOI: 10.1055/s-2007-994457

ORIGINAL ARTICLE

Coagulation Studies in Patients with Marked Thrombocytopenia due to Severe Preeclampsia

Jose A. Prieto, Joan M. Mastrobattista, Jorge D. Blanco

Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Texas Medical School at Houston, Lyndon Baines Johnson General Hospital, Houston, Texas

Abstract

ABSTRACT

From July 1, 1990, to July 1, 1993, we analyzed the results of fibrinogen levels, prothrombin time, and partial thromboplastin time in patients with severe preeclampsia, at least one platelet count less than 100,000/μL, and no signs of abruption or hemorrhage. Analysis was by Pearson's correlation coefficient and Wald's sequential analysis. We analyzed 162 blood collections from 48 patients. There was no correlation between the level of thrombocytopenia and the levels of prothrombin time, partial thromboplastin time, or fibrinogen. None of the samples from any of the preeclamptic patients demonstrated an abnormal prothrombin time or partial thromboplastin time.

Keywords

Thrombocytopenia - pregnancy - coagulation studies - preeclampsia

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