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Am J Perinatol 1994; 11(1): 14-18
DOI: 10.1055/s-2007-994525
ORIGINAL ARTICLE

© 1994 by Thieme Medical Publishers, Inc.

Ultrasound Placental Cysts Associated with Massive Placental Stem Villous Hydrops, Diploid DNA Content, and Exomphalos

B. R. Pridmore, T. Y. Khong, W. A. Wells
  • Department of Obstetrics and Gynaecology, The Queen Elizabeth Hospital, Woodville, South Australia (B.R.P.), Department of Pathology, Queen Victoria Hospital, Rose Park, South Australia (T.Y.K.), and Department of Pathology, Dartmouth-Hitchcock Medical Center, Hanover, New Hampshire (W.A.W.)
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Publication Date:
04 March 2008 (online)

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ABSTRACT

A pregnancy associated with antenatally detected placental cysts and an anterior abdominal wall defect is described. The anterior abdominal wall defect proved to be an exomphalos in which a short segment of normal cord intervened between the herniated sac and the cord insertion. The placental cysts detected antenatally by ultrasound were shown subsequently to be massive main stem villous hydrops with cisternal formation but no evidence of trophoblastic hyperplasia. Antenatal placental biopsy and amniocentesis revealed a normal male karyotype. Confined placental mosaicism for triploidy was excluded by DNA flow cytometry. This case was not associated with Beckwith-Wiedemann syndrome.