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Am J Perinatol 1985; 2(3): 208-210
DOI: 10.1055/s-2007-999950
ORIGINAL ARTICLE

© 1985 by Thieme Medical Publishers, Inc.

Isoimmunization in Pregnancy to Gerbich Antigen

David A. Sacks1 , Cage S. Johnson2 , Lawrence D. Platt3
  • 1Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Kaiser Permanente Medical Center, Bellflower, California
  • 2Division of Hematology, Department of Medicine, University of Southern California School of Medicine, Los Angeles, California
  • 3Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Southern California School of Medicine and Women's Hospital, Los Angeles County/USC Medical Center, Los Angeles, California
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Publikationsdatum:
04. März 2008 (online)

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ABSTRACT

A case of hemolytic disease of the newborn due to Gerbich, a public antigen, is presented. The antibody which was IgGI reacted in vitro with mononuclear phagocytes. Serial sonographic and amniotic fluid examinations were followed and a mildly jaundiced neonate was delivered. Further investigation may establish a relationship between severity of disease and IgG subclasses, a mononuclear phagocyte assay, and sonographic measurements. Sources of compatible blood for possible maternal, fetal, or neonatal transfusion include blood bank rare donor files, relatives, and autologous donation.