One-Pot Synthesis of 6-(Pyridyl)salicylates by Formal [3+3] Cyclizations of 1,3-Bis(silyl enol ethers) with 3-Pyridyl-3-silyloxy-2-en-1-ones

Mirza A. Yawer; Abdolmajid Riahi; Muhammad Adeel; Ibrar Hussain; Christine Fischer; Peter Langer

doi:10.1055/s-2008-1042949

PAPER

One-Pot Synthesis of 6-(Pyridyl)salicylates by Formal [3+3] Cyclizations of 1,3-Bis(silyl enol ethers) with 3-Pyridyl-3-silyloxy-2-en-1-ones

Mirza A. Yawer^a, Abdolmajid Riahi^a,b, Muhammad Adeel^a, Ibrar Hussain^a, Christine Fischer^b, Peter Langer*^a,b
^a Institut für Chemie, Universität Rostock, Albert Einstein Str. 3a, 18059 Rostock, Germany
^b Leibniz-Institut für Katalyse e.V. an der Universität Rostock, Albert Einstein Str. 29a, 18059 Rostock, Germany

Abstract

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Abstract

6-(Pyridyl)salicylates were regioselectively prepared by formal [3+3] cyclization of 1,3-bis(silyl enol ethers) with 3-(pyridyl)-3-silyloxy-2-en-1-ones. These reactions represent what are, to the best of our knowledge, the first [3+3] cyclizations of 1,3-bis(silyl enol ethers) with heterocyclic substrates.

Key words

cyclizations - heterocycles - regioselectivity - pyridines - silyl enol ethers

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Referenzen

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