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DOI: 10.1055/s-2008-1074547
© Georg Thieme Verlag KG Stuttgart · New York
Phytochemical Investigation of Anaphalis lactea
Publication History
Received: February 5, 2008
Revised: April 17, 2008
Accepted: April 19, 2008
Publication Date:
03 June 2008 (online)
Abstract
Four new compounds, 2′,6′-dihydroxy-3′-(2-hydroxy-3-methyl-3-butenyl)-4′-methoxychalcone (1), 4,6-dihydroxy-7-isobutyryl-5-prenyl-2(3H)-benzofuranone (4), 7-O-(β-D-glucopyranosyloxy)-5-hydroxy-1(3H)-isobenzofuranone (6) and (2R,3S)-3-methyl-2-(5-oxo-2-isopropenylhexyl)-cyclopentanone (7), along with thirteen known compounds were isolated from the whole plant of Anaphalis lactea. Their structures were established based on spectroscopic methods including IR, UV, MS, CD, 1 D NMR and 2 D NMR techniques. Compounds 2, 4 – 6 and 8 – 16 were tested for free-radical scavenging properties in the DPPH assays.
Key words
Anaphalis lactea - Compositae - chalcones - benzofuranones - phthalide glucosides - sesquiterpenes - antioxidant property
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Prof. Yan-Ping Shi, PhD
Key Laboratory for Natural Medicine of Gansu Province
Lanzhou Institute of Chemical Physics
Chinese Academy of Sciences
Lanzhou 730000
People’s Republic of China
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