Abstract
The phytochemical investigation of the acetone extract of the aerial parts of Elaeoselinum asclepium (L.) Bertol. subsp. meoides (Desf.) Fiori afforded several known diterpenoids as well as meoidic acid (5), new in the literature. The cytotoxic activities of elasclepic acid (1), ent-atis-16-en-19-oic acid (2), ent-beyer-15-en-19-oic acid (3), ent-kaur-16-en-19-oic acid (4) and meoidic acid (5) were investigated on rat glioma C6 cells by evaluation of cell growth inhibition.
Key words
Elaeoselinum asclepium subsp. meoides
- Umbelliferae - diterpenoids - meoidic acid - cytotoxic activity
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Prof. Maurizio Bruno
Dipartimento di Chimica Organica
Università degli Studi di Palermo
Viale delle Scienze
Parco d’Orleans II
90128 Palermo
Italy
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Fax: +39/091/596/825
Email: bruno@dicpm.unipa.it
