Subscribe to RSS
DOI: 10.1055/s-2008-1081088
© Georg Thieme Verlag KG Stuttgart · New York
Hämatologie 2008
Hematology 2008Publication History
Publication Date:
13 June 2008 (online)
Was ist neu?
-
Antikoagulation: Thromboseprophylaxe mit Rivaroxaban (M. Hellmann, M. Kochanek)
-
Eculizimab: Komplement-Inhibition als Therapie der paroxysmalen nächtlichen Hämoglobinurie (P. Borchmann)
-
Chronische lymphatische Leukämie: Therapiestrategie in Abhängigkeit von der Fitness des Patienten (B. Eichhorst, M. Hallek)
-
Multiples Myelom: Immunmodulation mit Lenalidomid (K. Hübel)
-
Myelodysplastisches Syndrom: Epigenetische Therapien (K. Kreuzer)
-
Indolente Lymphome: Ibritumomab-Tiuxetan/Bendamustin + Rituximab (M. Reiser)
-
Hodgkin Lymphom: Die Positronen-Emissions-Tomographie als Methode zur Therapieentscheidung (P. Borchmann)
-
Akute myeloische Leukämie: Molekulare Risikostratifizierung (K. Kreuzer)
Literatur
- 1 Agnelli G, Gallus A, Goldhaber S Z, Haas S, Huisman M V, Hull R D, Kakkar A K, Misselwitz F, Schellong S. et al, ODIXa-DVT Study Investigators . Treatment of proximal deep-vein thrombosis with the oral direct factor Xa inhibitor rivaroxaban (BAY 59 - 7939): the ODIXa-DVT (Oral Direct Factor Xa Inhibitor BAY 59 - 7939 in Patients with Acute Symptomatic Deep-Vein Thrombosis) study. Circulation. 2007; 116 180-187
- 2 Boultwood J, Wainscoat J S. Gene silencing by DNA methylation in haematological malignancies. Br J Haematol. 2007; 138 3-11
- 3 Brenner H, Gondos A, Pulte D. Trends in long-term survival of patients with chronic lymphocytic leukaemia from the 1980 s to the early 21st century. Blood. 2008;
- 4 Büller H R, Agnelli G. the EINSTEIN-DVT and ODIXa-DVT Study groups . Once or twice-daily rivaroxaban for the treatment of proximal deep vein thrombosis: similar efficiacy and safety to standard therapy in dose-ranging studies. Blood. 2006; 108
- 5 Catovsky D, Richards S, Matutes E. et al . Assessment of fludarabine plus cyclophosphamide for patients with chronic lymphocytic leukaemia (the LRF CLL4 Trial): a randomised controlled trial. Lancet. 2007; 370 230-239
- 6 Diehl V, Kobe C, Haverkamp H. et al . FDG-PET for Assessment of Residual Tissue after Completion of Chemotherapy in Hodgkin Lymphoma - Report on the 2nd Interim Analysis of the PET Investigation in the Trial HD15 of the GHSG. Blood (ASH Annual Meeting Abstracts). Nov 2007; 110 212
- 7 Dimopoulos M, Spencer A, Attal M. et al . Lenalidomide plus dexamethasone for relapsed or refractory multiple myeloma. N Engl J Med. 2007; 357 2123-2132
- 8 Eichhorst B F, Busch R, Stauch M. et al . No significant clinical benefit of fist line therapy with fludarabine (F) in comparison to chlorambucil (Clb) in elderly patients (pts) with advanced chronic lymphocytic leukaemia (CLL): results of a phase III study of the German CLL study group (GCLLSG). Blood. 2007; 110
- 9 Grövdal M, Khan R, Aggerholm A. et al . Negative effect of DNA hypermethylation on the outcome of intensive chemotherapy in older patients with high-risk myelodysplastic syndromes and acute myeloid leukemia following myelodysplastic syndrome. Clin Cancer Res. 2007; 13 7107-7112
- 10 Hagenbeek. et al . 90Y-Ibritumomab Tiuxetan (Zevalin) Consolidation of First Remission in Advanced Stage Follicular Non-Hodgkins Lymphoma: First Results of the International Randomized Phase 3 First-Line Indolent Trial (FIT) in 414 Patients. Blood. 2007; 110
- 11 Hagenbeek A, Bischof-Delaloye A, Radford J A. et al . 90Y-Ibritumomab Tiuxetan (Zevalin®) Consolidation of First Remission in Advanced Stage Follicular Non-Hodgkin’s Lymphoma: First Results of the International Randomized Phase 3 First-Line Indolent Trial (FIT) in 414 Patients. Blood (ASH Annual Meeting Abstracts). Nov 2007; 110 643
- 12 Hillmen P, Muus P, Duhrsen U. et al . Effect of the complement inhibitor eculizumab on thromboembolism in patients with paroxysmal nocturnal hemoglobinuria. Blood. 2007; 110 4123-4128
- 13 Hillmen P, Skotnicki A B, Robak T. et al . Alemtuzamab compared with chlorambucil as first-line therapy for chronic lymphocytic leukaemia. J Clin Oncol. 2007;
- 14 Hillmen P, Young N S, Schubert J. et al . The complement inhibitor eculizumab in paroxysmal nocturnal hemoglobinuria. N Engl J Med. 2006; 355 1233-1243
- 15 Kantarjian H, Issa J P, Rosenfeld C S. et al . Decitabine improves patient outcomes in myelodysplastic syndromes: results of a phase III randomized study. Cancer. 2006; 106 1794-1803
- 16 Kantarjian H M, O’Brien S, Shan J. et al . Update of the decitabine experience in higher risk myelodysplastic syndrome and analysis of prognostic factors associated with outcome. Cancer. 2007; 109 265-273
- 17 Kantarjian H M, Oki Y, Garcia-Manero G. et al . Results of a randomized study of 3 schedules of low-dose decitabine in higher-risk myelodysplastic syndrome and chronic myelomonocytic leukemia. Blood. 2007; 109 52-57
- 18 Knauf W, Lissichkov T. et al . Bendamustine versus Chlorambucin in treatment-naïve patients with B-cell chronic lymphocytic leukaemia (B-CLL): results of an international phase III study. Blood. 2007; 110
- 19 Lassen M R, Turpie A G, Rosencher N, Borris L C. et al . Rivaroxaban - an oral direct Factor Xa inhibitor - for thromboprophylaxis after total knee arthroplasty: the RECORD3 trial. Blood. 2007; 110
- 20 Lyons R, Cosgriff T, Modi S. et al . Azacytidine (Vidaza) treatment response assessed using three alternative dosing schedules in pat9ients with myelodysplastic syndromes. Blood. 2005; 106 707a
- 21 Oliansky D M, Appelbaum F, Cassileth P A. et al . The role of cytotoxic therapy with hematopoietic stem cell transplantation in the therapy of acute myelogenous leukemia in adults: an evidence-based review. Biol Blood Marrow Transplant. 2008; 14 137-180
- 22 Rajkumar S V, Jacobus S, Callander N. et al . A randomized trial of lenalidomide plus high-dose dexamethasone (RD) versus lenalidomide plus low-dose dexamethasone (Rd) in newly diagnosed multiple myeloma (E4A03): a trial coordinated by the Eastern Cooperative Oncology Group. Blood. 2007; 110 74
- 23 Rosse W F. et al . Immune-mediated hemolytic anemia. Hematology Am Soc Hematol Educ Program. 2004; 48-62
- 24 Rossetti J, Falke E, Shadduck. et al . G-CSF increases hematological responses among patients with myelodysplasia treated with azacitidine. Blood. 2006; 108 303b
- 25 Rummel. et al . Bendamustine Plus Rituximab Versus CHOP Plus Rituximab in the First-Line Treatment of Patients with Indolent and Mantle Cell Lymphomas First Interim Results of a Randomized Phase III Study of the StiL (Study Group Indolent Lymphomas, Germany). Blood. 2007; 110
- 26 Schnittger S, Schoch C, Dugas M. et al . Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease. Blood. 2002; 100 59-66
- 27 Schulz. et al . Immunochemotherapy with rituximab and overall survival in patients with indolent or mantle cell lymphoma: a systematic review and meta-analysis. J Natl Cancer Inst. 2007; 99 706-714
- 28 Silverman L R, McKenzie D R, Peterson B L. et al . Further analysis of trials with azacitidine in patients with myelodysplastic syndrome: studies 8421, 8921, and 9221 by the Cancer and Leukemia Group B. J Clin Oncol. 2006; 24 3895-3903
- 29 Weber D M, Chen C, Niesvizky R. et al . Lenalidomide plus dexamethasone for relapsed multiple myeloma in North America. N Engl J Med. 2007; 357 2133-2142
- 30 Zhang W, Konopleva M, Shi Y X. et al . Mutant FLT3: a direct target of sorafenib in acute myelogenous leukemia. J Natl Cancer Inst. 2008; 100 184-198
Prof. Dr. med. M. Hallek
Klinik I für Innere Medizin, Universitätsklinikum
Joseph-Stelzmann Str. 9
50924 Köln
Phone: 0221/4784400
Fax: 0221/4785455
Email: elisabeth.albrecht@uk-koeln.de