Thrombosis and Haemostasis, Table of Contents Thromb Haemost 2005; 93(01): 115-117DOI: 10.1160/TH04-02-0086 Platelets and Blood Cells Schattauer GmbH Effect of altitude on thrombopoietin and the platelet count in healthy volunteers Sabine Hartmann 1 Perinatal Research Unit, Department of Obstetrics, Zurich University Hospital, Switzerland , Alexander Krafft 1 Perinatal Research Unit, Department of Obstetrics, Zurich University Hospital, Switzerland , Renate Huch 1 Perinatal Research Unit, Department of Obstetrics, Zurich University Hospital, Switzerland , Christian Breymann 1 Perinatal Research Unit, Department of Obstetrics, Zurich University Hospital, Switzerland › Author Affiliations Recommend Article Abstract Full Text PDF Download Keywords KeywordsThrombopoietin - erythropoietin - hypoxia - altitude References References 1 Wolber EM, Jelkmann W. Thrombopoietin: the novel hepatic hormone. News Physiol Sci 2002; 17: 6-10. 2 Nagasawa T, Hasegawa Y, Shimizu S. et al Serum thrombopoietin level is mainly regulated by megakaryocyte mass rather than platelet mass in human subjects. Br J Haematol 1998; 101: 242-4. 3 Broudy VC, Lin NL, Sabath DF. et al Human platelets display high-affinity receptors for thrombopoietin. Blood 1997; 89: 1896-904. 4 Hudson JG. The effect of high altitude on platelet counts, thrombopoietin and erythropoietin levels in young Bolivian airmen visiting the Andes. Int J Biometeorol 1999; 43: 85-90. 5 Krafft A, Huch R, Hartmann S. et al Combined thrombopoietin and platelet response to altitude in a patient with autoimmune thrombocytopenia. Thromb Haemost 2004; 91: 626-7. 6 Chapman ES, Sorette M, Hetherington E. et al A rapid, automated flow cytometric method to measure activated degranulated platelets by density determination. Thromb Haemost 2003; 89: 1004-15. 7 Simon-Schnass I, Korniszewski L. The influence of vitamin E on rheological parameters in high altitude mountaineers. Int J Vitam Nutr Res 1990; 60: 26-34. 8 Jelkmann W. The role of the liver in the production of thrombopoietin compared with erythropoietin. Eur J Gastroenterol Hepatol 2001; 13: 791-801. 9 Levine BD, Stray-Gundersen J. "Living hightraining low": effect of moderate-altitude acclimatization with low-altitude training on performance. J Appl Physiol 1997; 83: 102-1.