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Thromb Haemost 2007; 97(04): 681-682
DOI: 10.1160/TH06-08-0467
Letters to the Editor
Schattauer GmbH

C-reactive protein and FcγRIIa functional polymorphisms are not associated with clinical presentation of stable and unstable angina

Andrew Murphy
1   Baker Heart Research Institute, Melbourne, Victoria, Australia
,
Anthony White
1   Baker Heart Research Institute, Melbourne, Victoria, Australia
,
Rajesh Nair
1   Baker Heart Research Institute, Melbourne, Victoria, Australia
,
Bronwyn Kingwell
1   Baker Heart Research Institute, Melbourne, Victoria, Australia
,
Stephen Duffy
1   Baker Heart Research Institute, Melbourne, Victoria, Australia
,
Jaye Chin-Dusting
1   Baker Heart Research Institute, Melbourne, Victoria, Australia
,
Kevin Woollard
1   Baker Heart Research Institute, Melbourne, Victoria, Australia
› Author Affiliations
Further Information

Publication History

Received 26 August 2006

Accepted after resubmission 03 January 2007

Publication Date:
24 November 2017 (online)

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  • References

  • 1 Verma S, Devaraj S, Jialal I. Is C-reactive protein an innocent bystander or proatherogenic culprit? C-reactive protein promotes atherothrombosis. Circulation 2006; 113: 2135-2150. discussion 50
    PubMedGoogle Scholar
  • 2 Woolard KJ, Fisch C, Newby R. et al. C-reactive protein mediates CD11b expression in monocytes through the non-receptor tyrosine kinase, Syk, and calcium mobilization but not through cytosolic peroxides. Inflamm Res 2005; 54: 485-492.
    CrossrefPubMedGoogle Scholar
  • 3 De Servi S, Mariani M, Mariani G. et al. C-reactive protein increase in unstable coronary disease cause or effect?. J Am Coll Cardiol 2005; 46: 1496-1502.
    CrossrefPubMedGoogle Scholar
  • 4 Stein MP, Edberg JC, Kimberly RP. et al. C-reactive protein binding to FcgammaRIIa on human monocytes and neutrophils is allele-specific. J Clin Invest 2000; 105: 369-376.
    CrossrefPubMedGoogle Scholar
  • 5 Clark MR, Clarkson SB, Goldstein IM. Molecular basis for a polymorphism involving Fc receptor II on human monocytes. Trans Assoc Am Physicians 1989; 102: 252-259.
    PubMedGoogle Scholar
  • 6 Szalai AJ, Wu J, Lange EM. et al. Single-nucleotide polymorphisms in the C-reactive protein (CRP) gene promoter that affect transcription factor binding, alter transcriptional activity, and associate with differences in baseline serum CRP level. J Mol Med 2005; 83: 440-447.
    CrossrefPubMedGoogle Scholar
  • 7 Carlson CS, Aldred SF, Lee PK. et al. Polymorphisms within the C-reactive protein (CRP) gene promoter region are associated with CRP levels. Am J Hum Genet 2005; 77: 64-77.
    CrossrefPubMedGoogle Scholar
  • 8 Kathiresan S, Larson MG, Vasan RS. et al. Contribution of clinical correlates and 13 C-reactive protein gene polymorphisms to interindividual variability in serum C-reactive protein level. Circulation 2006; 113: 1415-1423.
    CrossrefPubMedGoogle Scholar
  • 9 Braunwald E. Unstable angina. A classification. Circulation 1989; 80: 410-414.
    CrossrefPubMedGoogle Scholar
  • 10 Hamm CW, Braunwald E. A classification of unstable angina revisited. Circulation 2000; 102: 118-122.
    CrossrefPubMedGoogle Scholar
  • 11 Ben-Avi L, Durst R, Shpitzen S. et al. Apolipoprotein E genotyping: accurate, simple, high throughput method using ABI Prism SNaPshot Multiplex System. J Alzheimers Dis 2004; 6: 497-501.
    CrossrefPubMedGoogle Scholar
  • 12 Willerson JT. Systemic and local inflammation in patients with unstable atherosclerotic plaques. Prog Cardiovasc Dis 2002; 44: 469-478.
    CrossrefPubMedGoogle Scholar
  • 13 Gardemann A, Horstmann A, Santoso S. Fc ΥRIIa- R131H polymorphism: its impact on coronary heart disease in a German cohort. Thromb Haemost 2003; 90: 1218-1220.
    Article in Thieme ConnectPubMedGoogle Scholar