Gender as a risk factor for pulmonary embolism after air travel

Frédéric Lapostolle; Philippe Le Toumelin; Carine Chassery; Michel Galinski; Lydia Ameur; Patricia Jabre; Claude Lapandry; Frédéric Adnet

doi:10.1160/TH09-06-0407

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 2009; 102(06): 1165-1168
DOI: 10.1160/TH09-06-0407

Rapid and Short Communication

Schattauer GmbH

Gender as a risk factor for pulmonary embolism after air travel

Frédéric Lapostolle

¹SAMU 93, Hôpital Avicenne, Bobigny Cedex, France

,

Philippe Le Toumelin

¹SAMU 93, Hôpital Avicenne, Bobigny Cedex, France

,

Carine Chassery

¹SAMU 93, Hôpital Avicenne, Bobigny Cedex, France

,

Michel Galinski

¹SAMU 93, Hôpital Avicenne, Bobigny Cedex, France

,

Lydia Ameur

¹SAMU 93, Hôpital Avicenne, Bobigny Cedex, France

,

Patricia Jabre

¹SAMU 93, Hôpital Avicenne, Bobigny Cedex, France

,

Claude Lapandry

¹SAMU 93, Hôpital Avicenne, Bobigny Cedex, France

,

Frédéric Adnet

¹SAMU 93, Hôpital Avicenne, Bobigny Cedex, France

› Author Affiliations

Abstract

Summary

It was the objective of this study to confirm the hypothesis that women experience an increased risk of pulmonary embolism (PE) and/or thromboembolic events after long-distance air travel. We systematically reviewed the records of all patients with confirmed pulmonary embolism after arrival at Roissy-Charles-de-Gaulle (CDG) Airport (Paris, France) during a 13-year period.The incidence of PE was calculated as a function of distance travelled and gender using Bayesian conditional probabilities obtained in part from a control population of long-distance travellers arriving in French Polynesia (Tahiti). A total of 287.6 million passengers landed at CDG airport during the study period. The proportion of male to female long-distance travellers was estimated to be 50.5% to 49.5%. Overall, 116 patients experienced PE after landing [90 females (78%), 26 males (22%)]. The estimated incidence of PE was 0.61 (0.61–0.61) cases per million passengers in females and 0.2 (0.20–0.20) in males, and reached 7.24 (7.17–7.31) and 2.35 (2.33–2.38) cases, respectively, in passengers travelling over 10,000 km. Our study strongly suggests that there is a relationship between risk of PE after air travel and gender.This relationship needs to be confirmed in order to develop the best strategy for prophylaxis.

Keywords

Pulmonary embolism - risk factors - clinical studies

Full Text

References

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