Decreased protein Z levels in patients with rheumatoid arthritis: Links with inflammation

• References

• 1 Meune C, Touzé E, Trinquart L. et al. High risk of clinical cardiovascular events in rheumatoid arthritis: Levels of associations of myocardial infarction and stroke through a systematic review and metaanalysis. Arch Cardiovasc Dis 2010; 103: 253-261.
• 2 Matta F, Singala R, Yaekoub AY. et al. Risk of venous thromboembolism with rheumatoid arthritis. Thromb Haemost 2009; 101: 134-138.
• 3 Gabriel SE. Cardiovascular morbidity and mortality in rheumatoid arthritis. Am J Med 2008; 121: S9-14.
• 4 Kwasny-Krochin B, Gluszko P, Undas A. Unfavorably altered fibrin clot properties in patients with active rheumatoid arthritis. Thromb Res 2010; 126: e11-6.
• 5 Sattar N, McCarey DW, Capell H. et al. Explaining how „high-grade“ systemic inflammation accelerates vascular risk in rheumatoid arthritis. Circulation 2003; 108: 2957-2963.
• 6 Undas A, Gissel M, Kwasny-Krochin B. et al. Thrombin generation in rheumatoid arthritis: dependence on plasma factor composition. Thromb Haemost 2010; 104: 224-230.
• 7 Pardos-Gea J, Ordi-Ros J, Serrano S. et al. Protein Z levels and anti-protein Z antibodies in patients with arterial and venous thrombosis. Thromb Res 2008; 121: 727-734.
• 8 Vasse M. Protein Z, a protein seeking a pathology. Thromb Haemost 2008; 100: 548-556.
• 9 Sofi F, Cesari F, Abbate R. et al. A meta-analysis of potential risks of low levels of protein Z for diseases related to vascular thrombosis. Thromb Haemost 2010; 103: 749-756.
• 10 Undar L, Karadogan I, Oztürk F. Plasma protein Z levels inversely correlate with plasma interleukin-6 levels in patients with acute leukemia and non-Hodgkin’s lymphoma. Thromb Res 1999; 94: 131-134.
• 11 Vasse M, Denoyelle C, Legrand E. et al. Weak regulation of protein Z biosynthesis by inflammatory cytokines. Thromb Haemost 2002; 87: 350-351.
• 12 Ordóñez A, Yélamos J, Pedersen S. et al. Increased levels of citrullinated antithrombin in plasma of patients with rheumatoid arthritis and colorectal ade-nocarcinoma determined by a newly developed ELISA using a specific monoclonal antibody. Thromb Haemost 2010; 104: 1143-1149.
• 13 Ozkaya O, Bek K, Fisgin T. et al. Low protein Z levels in children with nephrotic syndrome. Pediatr Nephrol 2006; 21: 1122-1126.