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Thromb Haemost 2014; 112(02): 223
DOI: 10.1160/TH14-07-0583
DOI: 10.1160/TH14-07-0583
T&H Insights
CD40-CD40L: a Janus-faced interaction
Further Information
Publication History
Received:
04 July 2014
Accepted:
04 July 2014
Publication Date:
04 December 2017 (online)
Insight on ► Willecke et al. Thromb Haemost 2014; 112: 379-389.
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References
- 1 Engel D, Seijkens T, Poggi M. et al. The immunobiologiy of CD154-CD40-TRAF interactions in atherosclerosis. Semin Immunol 2009; 21: 308-312.
- 2 Wolf D, Hohmann JD, Wiedemann A. et al. Binding of CD40L to Mac-1’s I-domain involves the EQLKKSKTL motif and mediates leukocyte recruitment and atherosclerosis--but does not affect immunity and thrombosis in mice. Circ Res 2011; 109: 1269-1279.
- 3 Lutgens E, Lievens D, Beckers L. et al. Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile. J Exp Med 2010; 207: 391-404.
- 4 Willecke F, Tiwari S, Rupprecht B. et al. Interruption of classic CD40L–CD40 signalling but not of the novel CD40L–Mac-1 interaction limits arterial neointima formation in mice. Thromb Haemost 2014; 112: 379-389.