CC BY-NC-ND 4.0 · Arq Neuropsiquiatr 2016; 74(01): 83-84
DOI: 10.1590/0004-282X20150155
IMAGES IN NEUROLOGY

Sneddon syndrome – imaging findings

Síndrome de Sneddon – achados de imagem
Pedro Henrique Teixeira Junqueira
1   Hospital Santa Catarina, Sao Paulo SP, Brazil;
2   Hospital Beneficência Portuguesa de São Paulo, MedImagem, Sao Paulo SP, Brazil.
,
Paulo Puglia Jr
1   Hospital Santa Catarina, Sao Paulo SP, Brazil;
,
Lázaro Luís Faria do Amaral
1   Hospital Santa Catarina, Sao Paulo SP, Brazil;
2   Hospital Beneficência Portuguesa de São Paulo, MedImagem, Sao Paulo SP, Brazil.
,
Mauricio Hoshino
1   Hospital Santa Catarina, Sao Paulo SP, Brazil;
› Author Affiliations
 

The Sneddon syndrome is a rare clinical syndrome that associates strokes and livedo, etiologically related with the antiphospholipid antibody syndrome ([Figure 1])[1],[2],[3],[4],[5].

Zoom Image
Figure 1reticular livedo on limbs.

This 42 year-old woman with headache and right hemiparesis had a MRI that showed acute/ subacute ischemia in part of the territory of the left middle cerebral artery (MCA) and bi-hemispheric gliosis/ encephalomalacia ([Figure 2]). MR angiography showed normal cervical carotid and vertebral circulation, filling defect in M2 segment of the left MCA. Catheter angiography disclosed difuse cortical occlusive arteriopathy associated with a rich collateral cortical network. The M2 occlusion was reperfused, with infarct sign in its territory ([Figures 3] and [4]).

Zoom Image
Figure 2 AXIAL FLAIR (A e B) showing areas corresponding to bi-hemispheric gliosis / encephalomalacia and area of acute/ subacute ischemic stroke in part of the territory of the left MCA. AXIAL DIFFUSION (C and D) proves acute / subacute schemic stroke area.
Zoom Image
Figure 3Angiography early arterial phase: (A) right side apparently normal; (B) slow filling area (red circle) and luxury perfusion (arrow).
Zoom Image
Figure 4Angiography capillary phase (A, B and C): occlusions of distal vessels + prominent collateral circulation (arrows), best visualized in the enlarged images (B and C).

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Conflicts of interest:

There is no conflict of interest to declare.

  • References

  • 1 Maamar M, Rahmani M, Aidi S, Benabdeljlil M, El HassaniMy R, Jiddane M et al. [Sneddon’s syndrome: 15 cases with cerebral angiography]. Rev Neurol (Paris). 2007;163(8-9):809-16. French. doi:10.1016/S0035-3787(07)91463-0
  • 2 Marinho JL, Piovesan EJ, Leite Neto MP, Kotze LR, Noronha L, Twardowschy CA et al. Clinical, neurovascular and neuropathological features in Sneddon’s syndrome. ArqNeuropsiquiatr. 2007;65(2B):390-5. doi:10.1590/S0004-282X2007000300005
  • 3 Boesch SM, Plörer AL, Auer AJ, Poewe W, Aichner FT, Felber SR et al. The natural course of Sneddon syndrome: clinical and magnetic resonance imaging findings in a prospective six year observation study. J Neurol Neurosug Psychiatry. 2003;74(4):542-4. doi:10.1136/jnnp.74.4.542
  • 4 Stockhammer G, Felber SR, Zelger B, Sepp N, Birbamer GG, Fritsch PO et al. Sneddon’s syndrome: diagnosis by skin biopsy and MRI in 17 patients. Stroke.1993;24(5):685-90. doi:10.1161/01.STR.24.5.685
  • 5 Uthman, I.W., Khamashta, M.A. Livedo racemosa: a striking dermatological sign for the antiphospholipid syndrome [Editorial]. J Rheumatol. 2006;33(12):2379-82.

Address for correspondence

Pedro Henrique Teixeira Junqueira
Med Imagem, Hospital Beneficência Portuguesa de São Paulo; Rua Maestro Cardim, 407; 01323-000 São Paulo SP
Brasil   

Publication History

Received: 11 July 2015

Accepted: 04 August 2015

Article published online:
06 September 2023

© 2015. Academia Brasileira de Neurologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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  • References

  • 1 Maamar M, Rahmani M, Aidi S, Benabdeljlil M, El HassaniMy R, Jiddane M et al. [Sneddon’s syndrome: 15 cases with cerebral angiography]. Rev Neurol (Paris). 2007;163(8-9):809-16. French. doi:10.1016/S0035-3787(07)91463-0
  • 2 Marinho JL, Piovesan EJ, Leite Neto MP, Kotze LR, Noronha L, Twardowschy CA et al. Clinical, neurovascular and neuropathological features in Sneddon’s syndrome. ArqNeuropsiquiatr. 2007;65(2B):390-5. doi:10.1590/S0004-282X2007000300005
  • 3 Boesch SM, Plörer AL, Auer AJ, Poewe W, Aichner FT, Felber SR et al. The natural course of Sneddon syndrome: clinical and magnetic resonance imaging findings in a prospective six year observation study. J Neurol Neurosug Psychiatry. 2003;74(4):542-4. doi:10.1136/jnnp.74.4.542
  • 4 Stockhammer G, Felber SR, Zelger B, Sepp N, Birbamer GG, Fritsch PO et al. Sneddon’s syndrome: diagnosis by skin biopsy and MRI in 17 patients. Stroke.1993;24(5):685-90. doi:10.1161/01.STR.24.5.685
  • 5 Uthman, I.W., Khamashta, M.A. Livedo racemosa: a striking dermatological sign for the antiphospholipid syndrome [Editorial]. J Rheumatol. 2006;33(12):2379-82.

Zoom Image
Figure 1reticular livedo on limbs.
Zoom Image
Figure 2 AXIAL FLAIR (A e B) showing areas corresponding to bi-hemispheric gliosis / encephalomalacia and area of acute/ subacute ischemic stroke in part of the territory of the left MCA. AXIAL DIFFUSION (C and D) proves acute / subacute schemic stroke area.
Zoom Image
Figure 3Angiography early arterial phase: (A) right side apparently normal; (B) slow filling area (red circle) and luxury perfusion (arrow).
Zoom Image
Figure 4Angiography capillary phase (A, B and C): occlusions of distal vessels + prominent collateral circulation (arrows), best visualized in the enlarged images (B and C).