CC BY-NC-ND 4.0 · Indian J Plast Surg 2014; 47(03): 370-374
DOI: 10.4103/0970-0358.146593
Original Article
Association of Plastic Surgeons of India

Effect of green tea on the second degree burn wounds in rats

Mohammad Javad Fatemi
Departments of Plastic and Reconstructive Surgery, Hazrat Fateme Hospital and Burn Research Center, Iran University of Medical Sciences, Tehran, Iran
,
Babak Nikoomaram
1   Department of Plastic and Reconstructive Surgery, Azad University of Medical Sciences, Tehran, Iran
,
Amir Asadollah Khajeh Rahimi
1   Department of Plastic and Reconstructive Surgery, Azad University of Medical Sciences, Tehran, Iran
,
Donya Talayi
1   Department of Plastic and Reconstructive Surgery, Azad University of Medical Sciences, Tehran, Iran
,
Shahrzad Taghavi
1   Department of Plastic and Reconstructive Surgery, Azad University of Medical Sciences, Tehran, Iran
,
Yaser Ghavami
Departments of Plastic and Reconstructive Surgery, Hazrat Fateme Hospital and Burn Research Center, Iran University of Medical Sciences, Tehran, Iran
› Author Affiliations
Further Information

Address for correspondence:

Dr. Mohammad Javad Fatemi
Department of Plastic and Reconstructive Surgery, Hazrat Fateme Hospital and Burn Research Center, Iran University of Medical Science
Vali-asr Ave., Yasami St., Tehran 19967 14353
Iran   

Publication History

Publication Date:
26 August 2019 (online)

 

ABSTRACT

Background: Various studies indicate that the green tea has anti-inflammatory and anti-oxidative properties. Moreover, a few studies have been carried out that demonstrate beneficial effects of green tea on burned patients. Materials and Methods: In this study, green tea, Vaseline, and silver sulfadiazine dressings were used as first-aid treatment to deep dermal contact burns in rats, compared with a control of nothing. After creating second-degree burn on the dorsum of rats, the treatments were applied for 15 min in four groups. Wound dressing changes were daily. Macroscopic study was performed on days 1, 3, 7, and 14 by using a digital camera and software processing of photos. Microscopic examination was done by pathologic evaluation of skin specimens on day 14. Results: We observed that green tea usage significantly decreased burn size in comparison to the control group (P = 0.004). Conclusion: Green tea is effective on healing process of second degree burn wounds.


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Conflict of Interest

None declared.

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  • 2 Fauerbach JA, Lezotte D, Hills RA, Cromes GF, Kowalske K, de Lateur BJ. et al. Burden of burn: A norm-based inquiry into the influence of burn size and distress on recovery of physical and psychosocial function. J Burn Care Rehabil 2005; 26: 21-32
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  • 15 Yamabe N, Yokozawa T, Oya T, Kim M. Therapeutic potential of (−)-epigallocatechin 3-O-gallate on renal damage in diabetic nephropathy model rats. J Pharmacol Exp Ther 2006; 319: 228-36
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  • 17 Sevin A, Oztas P, Senen D, Han U, Karaman C, Tarimci N. et al. Effects of polyphenols on skin damage due to ultraviolet A rays: An experimental study on rats. J Eur Acad Dermatol Venereol 2007; 21: 650-6
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Address for correspondence:

Dr. Mohammad Javad Fatemi
Department of Plastic and Reconstructive Surgery, Hazrat Fateme Hospital and Burn Research Center, Iran University of Medical Science
Vali-asr Ave., Yasami St., Tehran 19967 14353
Iran   

  • REFERENCES

  • 1 Mobley C, Sugarman JR, Deam C, Giles L. Prevalence of risk factors for residential fire and burn injuries in an American Indian community. Public Health Rep 1994; 109: 702-5
  • 2 Fauerbach JA, Lezotte D, Hills RA, Cromes GF, Kowalske K, de Lateur BJ. et al. Burden of burn: A norm-based inquiry into the influence of burn size and distress on recovery of physical and psychosocial function. J Burn Care Rehabil 2005; 26: 21-32
  • 3 Forjuoh SN, Guyer B, Ireys HT. Burn-related physical impairments and disabilities in Ghanaian children: Prevalence and risk factors. Am J Public Health 1996; 86: 81-3
  • 4 Wisely JA, Wilson E, Duncan RT, Tarrier N. Pre-existing psychiatric disorders, psychological reactions to stress and the recovery of burn survivors. Burns 2010; 36: 183-91
  • 5 Vinson JA, Teufel K, Wu N. Green and black teas inhibit atherosclerosis by lipid, antioxidant, and fibrinolytic mechanisms. J Agric Food Chem 2004; 52: 3661-5
  • 6 Jun X, Deji S, Ye L, Rui Z. Comparison of in vitro antioxidant activities and bioactive components of green tea extracts by different extraction methods. Int J Pharm 2011; 408: 97-101
  • 7 Chen H, Qu Z, Fu L, Dong P, Zhang X. Physicochemical properties and antioxidant capacity of 3 polysaccharides from green tea, oolong tea, and black tea. J Food Sci 2009; 74: C469-74
  • 8 Yuan JM. Green tea and prevention of esophageal and lung cancers. Mol Nutr Food Res 2011; 55: 886-904
  • 9 Luo XY, Li NN, Liang YR. Effects of Ilex latifolia and Camellia sinensis on cholesterol and circulating immune complexes in rats fed with a high-cholesterol diet. Phytother Res 2013; 27: 62-5
  • 10 Bogdanski P, Suliburska J, Szulinska M, Stepien M, Pupek-Musialik D, Jablecka A. Green tea extract reduces blood pressure, inflammatory biomarkers, and oxidative stress and improves parameters associated with insulin resistance in obese, hypertensive patients. Nutr Res 2012; 32: 421-7
  • 11 Ostertag LM, O’Kennedy N, Kroon PA, Duthie GG, de Roos B. Impact of dietary polyphenols on human platelet function: A critical review of controlled dietary intervention studies. Mol Nutr Food Res 2010; 54: 60-81
  • 12 Camouse MM, Domingo DS, Swain FR, Conrad EP, Matsui MS, Maes D. et al. Topical application of green and white tea extracts provides protection from solar-simulated ultraviolet light in human skin. Exp Dermatol 2009; 18: 522-6
  • 13 Elmets CA, Singh D, Tubesing K, Matsui M, Katiyar S, Mukhtar H. Cutaneous photoprotection from ultraviolet injury by green tea polyphenols. J Am Acad Dermatol 2001; 44: 425-32
  • 14 Zhen MC, Huang XH, Wang Q, Sun K, Liu YJ, Li W. et al. Green tea polyphenol epigallocatechin-3-gallate suppresses rat hepatic stellate cell invasion by inhibition of MMP-2 expression and its activation. Acta Pharmacol Sin 2006; 27: 1600-7
  • 15 Yamabe N, Yokozawa T, Oya T, Kim M. Therapeutic potential of (−)-epigallocatechin 3-O-gallate on renal damage in diabetic nephropathy model rats. J Pharmacol Exp Ther 2006; 319: 228-36
  • 16 Klass BR, Branford OA, Grobbelaar AO, Rolfe KJ. The effect of epigallocatechin-3-gallate, a constituent of green tea, on transforming growth factor-beta1-stimulated wound contraction. Wound Repair Regen 2010; 18: 80-8
  • 17 Sevin A, Oztas P, Senen D, Han U, Karaman C, Tarimci N. et al. Effects of polyphenols on skin damage due to ultraviolet A rays: An experimental study on rats. J Eur Acad Dermatol Venereol 2007; 21: 650-6
  • 18 Hong YH, Jung EY, Shin KS, Kim TY, Yu KW, Chang UJ. et al. Photoprotective effects of a formulation containing tannase-converted green tea extract against UVB-induced oxidative stress in hairless mice. Appl Biochem Biotechnol 2012; 166: 165-75