DOI: 10.1055/s-00000077

Seminars in Thrombosis and Hemostasis

Issue S 01 · Volume 34 · October 2008 DOI: 10.1055/s-002-13710 Landmarks in Anti-Thrombin Drug Development: The Argatroban Story Jeanine M Walenga Ph.D. Henri Bounameaux M.D. Yasuo Ikeda M.D.

PREFACE

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Walenga, Jeanine M.; Bounameaux, Henri; Ikeda, Yasuo: Landmarks in Anti-Thrombin Drug Development: The Argatroban Story

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Markwardt, Fritz: FOREWORD
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Fareed, Jawed; Walenga, Jeanine M.: A Tribute to Professor Hans Klaus Breddin
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Ikeda, Yasuo; Wanaka, Keiko; Okamoto, Utako: Okamoto's Strategy to Develop Argatroban: An Innovative Concept for the Future
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Bounameaux, Henri: Overview of Direct Thrombin Inhibitors in Clinical Practice
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Vissac, Anne Marie; Amiral, Jean: Mechanisms Involved in Heparin-Induced Thrombocytopenia and Associated Thrombosis
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Gruel, Yves; Pouplard, Claire: Overview of Heparin-Induced Thrombocytopenia. Diagnosis and Treatment in Europe with an Emphasis on France
037
Miyata, Shigeki; Yamamoto, Haruko; Kamei, Masataka; Nakatani, Takeshi; Kobayashi, Junjiro; Tsuji, Tetsu; Minematsu, Kazuo; Tomoike, Hitonobu: Heparin-Induced Thrombocytopenia Clinical Studies and the Efficacy of Argatroban in Japan
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Dempfle, Carl-Erik: Clinical Experience of Argatroban in Germany
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Koster, Andreas; Fischer, Karl-Georg: Argatroban Anticoagulation in Patients following Cardiovascular Surgery and in ICU Patients with and without Renal-Replacement Therapy
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Matsuo, Takefumi; Wanaka, Keiko: Hemodialysis and Argatroban
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Iqbal, Omer; Adiguzel, Cafer; Lewis, Bruce E.; Cunanan, Josephine; Fareed, Jawed: Argatroban for Percutaneous Coronary Interventions
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Harder, Sebastian; Koster, Andreas; Klinkhardt, Ute: The Direct Thrombin Inhibitor Argatroban: A Review of Its Pharmacokinetics and Pharmacokinetic/Pharmacodynamic Relationships
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Nowak, Götz; Lange, Ute; Bucha, Elke: Drug Monitoring of Argatroban Using the Ecarin Chromogenic Assay
087
Samama, Meyer Michel; Le Flem, Léna; Guinet, Céline; Depasse, François: Effect of Argatroban versus Recombinant Hirudin on Tissue-Factor-Mediated Thrombin Generation: An in Vitro Study
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He, Shu; Wallen, Håkan; Johnsson, Hans; Blombäck, Margareta: In Vitro Effects of Argatroban, Lepirudin, Bivalirudin, and Danaparoid on Fibrin Gel Permeability
097
Hoppensteadt, Debra A.; Jeske, Walter; Walenga, Jeanine M.; Bick, Rodger L.; Fareed, Jawed: The Anti-Inflammatory Effects of Argatroban Can Be Differentiated from Other Direct Thrombin Inhibitors: Experimental and Clinical Observations
103
Lopez, Mercedes; Nowak, Götz: Influence of Renal and Hepatic Failure on the Pharmacokinetics of Argatroban: An Experimental Study in Rats
108
Adiguzel, Cafer; Iqbal, Omer; Cunanan, Josephine; Jeske, Walter; Hoppensteadt, Debra; Walenga, Jeanine M.; Fareed, Jawed: Potency Adjusted Generic Versions of Argatroban Can Be Differentiated from Branded Argatroban in Thrombin Generation and Platelet Activation Assays
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Fareed, Jawed; Walenga, Jeanine M.; Jeske, Walter P.; Hoppensteadt, Debra; Prechel, Margaret; Iqbal, Omer; Adiguzel, Cafer; Clark, Melanie; Litinas, Evangelos; Cunanan, Josephine; Linhardt, Robert; Harenberg, Job: Biological Profile of the Hyper/Oversulfated Chondroitin Sulfate Contaminant Isolated from Recalled Heparin
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Fareed, Jawed; Walenga, Jeanine M.; Hoppensteadt, Debra A.; Bick, Rodger L.; Messmore, Harry L.: Dr. Eberhard F. Mammen Remembered: A Great Clinician-Scientist, Mentor, and Friend