DOI: 10.1055/s-00035024

Thrombosis and Haemostasis

Issue 03 · Volume 119 · March 2019 DOI: 10.1055/s-009-42535

Invited Editorial Focus

353
Semple, John W.; Kapur, Rick: The Ultimate Murine Model of Immune Thrombocytopaenia
355
Borer, Jeffrey S.; Atar, Dan; Marciniak, Thomas; Kim, Moo Hyun; Serebruany, Victor: Atrial Fibrillation and Stroke in Patients with Hypertrophic Cardiomyopathy: Important New Insights

Invited T&H Insights

358
Sajib, Md Sanaullah; Mikelis, Constantinos M.: DNA Repair Response Adaptors: Novel Targets for Vasoproliferative Retinopathy?

Review Article

359
Paciullo, Francesco; Momi, Stefania; Gresele, Paolo: PCSK9 in Haemostasis and Thrombosis: Possible Pleiotropic Effects of PCSK9 Inhibitors in Cardiovascular Prevention

Coagulation and Fibrinolysis

368
Stemberger, Michaela; Kallenbach, Felix; Schmit, Elisabeth; McEneny-King, Alanna; Germini, Federico; Yeung, Cindy H. T.; Edginton, Andrea N.; von Mackensen, Sylvia; Kurnik, Karin; Iorio, Alfonso: Impact of Adopting Population Pharmacokinetics for Tailoring Prophylaxis in Haemophilia A Patients: A Historically Controlled Observational Study
Supplementary Material

Cellular Haemostasis and Platelets

377
Li, Xin; Wang, Shu-wen; Feng, Qi; Hou, Yu; Lu, Nan; Ma, Chun-hong; Gao, Cheng-jiang; Hou, Ming; Peng, Jun: Novel Murine Model of Immune Thrombocytopaenia through Immunized CD41 Knockout Mice
Supplementary Material
384
Elaïb, Ziane; Lopez, Jose Javier; Coupaye, Muriel; Zuber, Kevin; Becker, Yann; Kondratieff, Aurélie; Repérant, Christelle; Pépin, Marion; Salomon, Laurence; Teillet, France; Msika, Simon; Denis, Cécile V.; de Prost, Dominique; Rosa, Jean-Philippe; Bobe, Régis; Stépanian, Alain: Platelet Functions are Decreased in Obesity and Restored after Weight Loss: Evidence for a Role of the SERCA3-Dependent ADP Secretion Pathway
Supplementary Material
397
Denzinger, Viola; Busygina, Kristina; Jamasbi, Janina; Pekrul, Isabell; Spannagl, Michael; Weber, Christian; Lorenz, Reinhard; Siess, Wolfgang: Optimizing Platelet GPVI Inhibition versus Haemostatic Impairment by the Btk Inhibitors Ibrutinib, Acalabrutinib, ONO/GS-4059, BGB-3111 and Evobrutinib
407
Handtke, Stefan; Steil, Leif; Palankar, Raghavendra; Conrad, Jane; Cauhan, Simran; Kraus, Luise; Ferrara, Myriam; Dhople, Vishnu; Wesche, Jan; Völker, Uwe; Greinacher, Andreas; Thiele, Thomas: Role of Platelet Size Revisited—Function and Protein Composition of Large and Small Platelets
Supplementary Material

Blood Cells, Inflammation and Infection

421
Yao, Xiaolan; Chen, Wenpei; Liu, Jin; Liu, Han; Zhan, Janis Y.; Guan, Shixia; Lu, Ziqi; Tang, Ping; Li, Peng; Lin, Baoqin: Deep Vein Thrombosis is Modulated by Inflammation Regulated via Sirtuin 1/NF-κB Signalling Pathway in a Rat Model
Supplementary Material
431
Asfari, Ahmed; Dent, Judith A.; Corken, Adam; Herington, Danielle; Kaliki, Vamsikrishna; Sra, Natasha; Hefley, Glenda; Pasala, Sanjiv; Prodhan, Parthak; Ware, Jerry: Platelet Glycoprotein VI Haplotypes and the Presentation of Paediatric Sepsis
Supplementary Material

Endothelium and Angiogenesis

439
Troullinaki, Maria; Garcia-Martin, Ruben; Sprott, David; Klotzsche-von Ameln, Anne; Grossklaus, Sylvia; Mitroulis, Ioannis; Chavakis, Triantafyllos; Economopoulou, Matina: 53BP1 Deficiency Promotes Pathological Neovascularization in Proliferative Retinopathy
Supplementary Material

Stroke, Systemic or Venous Thromboembolism

449
Li, Lei; Wu, Xi; Wu, Wenman; Ding, Qiulan; Cai, Xiaohong; Wang, Xuefeng: Clinical Manifestation and Mutation Spectrum of 53 Unrelated Pedigrees with Protein S Deficiency in China
Supplementary Material
461
Cohen, Alexander T.; Agnelli, Giancarlo; Buller, Harry R.; Gallus, Alexander; Raskob, Gary E.; Sanders, Paul; Thompson, John; Weitz, Jeffrey I.: Characteristics and Outcomes in Patients with Venous Thromboembolism Taking Concomitant Anti-Platelet Agents and Anticoagulants in the AMPLIFY Trial
Supplementary Material
467
Nakano, Takafumi; Nakamura, Yoshihiko; Matsuyama, Kiyoshi; Irie, Keiichi; Yasumura, Mako; Hirata, Yurie; Yamasaki, Motoki; Misumi, Kanae; Yamashita, Yuta; Myose, Takayuki; Matsuo, Koichi; Sano, Kazunori; Kamimura, Hidetoshi; Ishikura, Hiroyasu; Egawa, Takashi; Mishima, Kenichi: Long-Term Treatment with Thrombomodulin Improves Functional Outcomes after Cerebral Ischemia Even if Administration is Delayed
Supplementary Material
479
Duffett, Lisa; Kearon, Clive; Rodger, Marc; Carrier, Marc: Treatment of Superficial Vein Thrombosis: A Systematic Review and Meta-Analysis
Supplementary Material
490
Rézig, Shéhérazade; Mao, Raphael Le; Couturaud, Francis; Lacut, Karine; Delluc, Aurélien: Incidence of Cancer after a Second Unprovoked Venous Thromboembolic Event

Letter to the Editor

496
Violi, Francesco; Corazza, Gino Roberto; Caldwell, Stephen H.; Talerico, Giovanni; Romiti, Giulio Francesco; Napoleone, Laura; Perticone, Francesco; Bolondi, Luigi; Pietrangelo, Antonello; Vestri, Anna Rita; Raparelli, Valeria; Basili, Stefania; on behalf of PRO-LIVER Collaborative Group: Incidence and Recurrence of Portal Vein Thrombosis in Cirrhotic Patients
Supplementary Appendix

Trial Protocol Design Paper

500
Arnold, Donald M.; Jamula, Erin; Heddle, Nancy M.; Cook, Richard J.; Hsia, Cyrus; Sholzberg, Michelle; Lin, Yulia; Kassis, Jeannine; Blostein, Mark; Larratt, Loree; Amini, Sufia; Schipperus, Martin; Carruthers, Julie; Lane, Shannon J.; Li, Na; Kelton, John G.: Peri-Operative Eltrombopag or Immune Globulin for Patients with Immune Thrombocytopaenia (The Bridging ITP Trial): Methods and Rationale