DOI: 10.1055/s-00035024

Thrombosis and Haemostasis

Issue 04 · Volume 122 · April 2022 DOI: 10.1055/s-012-53549

Invited Editorial Focus

471
Ritchie, Leona A.; Penson, Peter E.; Lane, Deirdre A.: Warfarin—Is Self-Care the Best Care?

Invited T&H Insights

475
Geisler, Tobias: Insights into Release of Interleukin-1β from Platelets

Invited Mini Series: Novel Clinical Concepts in Thrombosis

476
McCutcheon, Keir; Manga, Pravin: Human Immunodeficiency Virus and Cardiovascular Disease: Revisiting the Inflammation–Thrombosis Axis

Review Article

480
Kanji, Rahim; Vandenbriele, Christophe; Arachchillage, Deepa R. J.; Price, Susanna; Gorog, Diana Adrienne: Optimal Tests to Minimise Bleeding and Ischaemic Complications in Patients on Extracorporeal Membrane Oxygenation

Coagulation and Fibrinolysis

492
Dhippayom, Teerapon; Boonpattharatthiti, Kansak; Thammathuros, Treeluck; Dilokthornsakul, Piyameth; Sakunrag, Itsarawan; Devine, Beth: Clinical Outcomes of Different Warfarin Self-Care Strategies: A Systematic Review and Network Meta-Analysis
Supplementary Material
506
Bianchini, Elsa P.; Razanakolona, Mahita; Helms, Julie; Zouiti, Fouzia; Couteau-Chardon, Amélie; Marin-Esteban, Viviana; Chaisemartin, Luc de; De-Carvalho, Allan; Bironien, Roselyne; Chollet-Martin, Sylvie; Denis, Cécile V.; Diehl, Jean-Luc; Vasse, Marc; Meziani, Ferhat; Borgel, Delphine: The Proteolytic Inactivation of Protein Z-Dependent Protease Inhibitor by Neutrophil Elastase Might Promote the Procoagulant Activity of Neutrophil Extracellular Traps in Sepsis
Supplementary Material

Cellular Haemostasis and Platelets

517
Pennings, Gabrielle J.; Reddel, Caroline J.; Traini, Mathew; Lam, Magdalena; Kockx, Maaike; Chen, Vivien M.; Kritharides, Leonard: Rapid Release of Interleukin-1β from Human Platelets Is Independent of NLRP3 and Caspase
Supplementary Material
529
Vadaq, Nadira; Schirmer, Melanie; Tunjungputri, Rahajeng N.; Vlamakis, Hera; Chiriac, Cecilia; Ardiansyah, Edwin; Gasem, M. Hussein; Joosten, Leo A. B.; de Groot, Philip G.; Xavier, Ramnik J.; Netea, Mihai G.; van der Ven, Andre J.; de Mast, Quirijn: Untargeted Plasma Metabolomics and Gut Microbiome Profiling Provide Novel Insights into the Regulation of Platelet Reactivity in Healthy Individuals
Supplementary Material

Blood Cells, Inflammation and Infection

540
Grimnes, Gro; Bhoelan, Soerajja; Hindberg, Kristian; Davids, Mark; Nieuwdorp, Max; Mollnes, Tom E.; Michelsen, Annika E.; Ueland, Thor; Brækkan, Sigrid K.; Hansen, John-Bjarne; Tichelaar, Vladimir: Impact of a Vancomycin-Induced Shift of the Gut Microbiome in a Gram-Negative Direction on Plasma Factor VIII:C Levels: Results from a Randomized Controlled Trial

New Technologies, Diagnostic Tools and Drugs

552
Lindhoff-Last, Edelgard; Birschmann, Ingvild; Kuhn, Joachim; Lindau, Simone; Konstantinides, Stavros; Grottke, Oliver; Nowak-Göttl, Ulrike; Lucks, Jessica; Zydek, Barbara; von Heymann, Christian; Sümnig, Ariane; Beyer-Westendorf, Jan; Schellong, Sebastian; Meybohm, Patrick; Greinacher, Andreas; Herrmann, Eva; On behalf of the RADOA-Registry Investigators (Reversal Agent use in patients treated with Direct Oral Anticoagulants or vitamin K antagonists Registry): Pharmacokinetics of Direct Oral Anticoagulants in Emergency Situations: Results of the Prospective Observational RADOA-Registry
Supplementary Material

Stroke, Systemic or Venous Thromboembolism

560
Frischmuth, Tobias; Hindberg, Kristian; Aukrust, Pål; Ueland, Thor; Brækkan, Sigrid K.; Hansen, John-Bjarne; Morelli, Vânia M.: Plasma Levels of Leptin and Risk of Future Incident Venous Thromboembolism
Supplementary Material
570
Mora, Damián; Nieto, José A.; Mateo, Jorge; Bikdeli, Behnood; Barco, Stefano; Trujillo-Santos, Javier; Soler, Silvia; Font, Llorenç; Bosevski, Marijan; Monreal, Manuel; the RIETE Investigators: Machine Learning to Predict Outcomes in Patients with Acute Pulmonary Embolism Who Prematurely Discontinued Anticoagulant Therapy
Supplementary Material
578
Bonnesen, Kasper; Schmidt, Morten; Horváth-Puhó, Erzsébet; Sørensen, Henrik T.: The Interaction Effect between Comorbidity Burden and Venous Thromboembolism on Mortality: A Nationwide Cohort Study
Supplementary Material
590
Noumegni, Steve Raoul; Hoffmann, Clément; Tromeur, Cécile; Didier, Romain; Bressollette, Luc; Lacut, Karine; Couturaud, Francis: Risk Factors of Arterial Events in Patients with Venous Thromboembolism: A Systematic Review and Meta-Analysis
Supplementary Material
600
van de Brug, Anouk; de Winter, Maria A.; ten Wolde, Marije; Kaasjager, Karin; Nijkeuter, Mathilde: Deciding on Treatment Duration for Unprovoked Venous Thromboembolism: What is Important to Patients?
Supplementary Material
611
Popa, Miruna; Hecker, Markus; Wagner, Andreas H.: Inverse Regulation of Confluence-Dependent ADAMTS13 and von Willebrand Factor Expression in Human Endothelial Cells
Supplementary Material
623
Grosse, Gerrit M.; Werlein, Christopher; Blume, Nicole; Abu-Fares, Omar; Götz, Friedrich; Gabriel, Maria M.; Ernst, Johanna; Leotescu, Andrei; Worthmann, Hans; Kühnel, Mark P.; Jonigk, Danny D.; Falk, Christine S.; Weissenborn, Karin; Schuppner, Ramona: Circulating Cytokines and Growth Factors in Acute Cerebral Large Vessel Occlusion—Association with Success of Endovascular Treatment
Supplementary Material
633
Riedl, Jakob M.; Schwarzenbacher, Esther; Moik, Florian; Horvath, Lena; Gantschnigg, Antonia; Renneberg, Felix; Posch, Florian; Barth, Dominik A.; Stotz, Michael; Pichler, Martin; Hatzl, Stefan; Fandler-Höfler, Simon; Gressenberger, Paul; Gary, Thomas; Jost, Philipp J.; Greil, Richard; Ay, Cihan; Djanani, Angela; Gerger, Armin; Schlick, Konstantin: Patterns of Thromboembolism in Patients with Advanced Pancreatic Cancer Undergoing First-Line Chemotherapy with FOLFIRINOX or Gemcitabine/nab-Paclitaxel
Supplementary Material

Trial Protocol Design Paper

646
Mahé, Isabelle; Agnelli, Giancarlo; Ay, Cihan; Bamias, Aristotelis; Becattini, Cecilia; Carrier, Marc; Chapelle, Céline; Cohen, Alexander T.; Girard, Philippe; Huisman, Menno V.; Klok, Frederikus A.; López-Núñez, Juan J.; Maraveyas, Anthony; Mayeur, Didier; Mir, Olivier; Monreal, Manuel; Righini, Marc; Samama, Charles M.; Syrigos, Kostas; Szmit, Sebastian; Torbicki, Adam; Verhamme, Peter; Vicaut, Eric; Wang, Tzu-Fei; Meyer, Guy; Laporte, Silvy: Extended Anticoagulant Treatment with Full- or Reduced-Dose Apixaban in Patients with Cancer-Associated Venous Thromboembolism: Rationale and Design of the API-CAT Study
Supplementary Material