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DOI: 10.1055/s-0042-1757275
COVID-19 Vaccine Acceptance in Pregnancy
Funding None.Abstract
Objective The purpose of the study is to evaluate the acceptance rate of the coronavirus disease 2019 (COVID-19) vaccine among pregnant women at our institution prior to recommendations by national organizations (American College of Obstetricians and Gynecologists/The Society for Maternal-Fetal Medicine) in July 2021 and to determine whether factors including health disparities are associated with acceptance.
Study Design This is an Institutional Review Board exempt descriptive study. Anonymous surveys were administered from February 2021 to May 2021 to pregnant patients at Mount Sinai South Nassau's affiliated Maternal Fetal Medicine office. The survey was completed by 701 pregnant women. Descriptive statistics were calculated for the overall sample, as well as separately by group (acceptance versus declining/undecided about getting the COVID-19 vaccine). The two groups were compared using the chi-square test or Fisher's exact test and the two-sample t-test. Analysis was compared between two groups (patients who accepted the COVID-19 vaccine and people who declined/undecided about the vaccine). A result was considered statistically significant at the p < 0.05 level of significance.
Results Of the 701 pregnant women who completed the survey, 96 patients accepted the vaccine. More pregnant women who were older accepted the COVID-19 vaccine compared with those who were younger (p = 0.0343). Pregnant women willing to get the flu vaccine and/or the Tdap vaccine in pregnancy were more likely to obtain the COVID-19 vaccine (p < 0.05). Pregnant patients who had household members willing to receive the COVID-19 vaccine sought to obtain the vaccine for themselves (p < 0.0001). Interestingly, pregnant women who had an underlying respiratory illness in the pregnancy were less likely to accept the COVID-19 vaccine than those who had either other or no medical problems (p < 0.05).
Conclusion There is a low rate of COVID-19 vaccine acceptance among pregnant women (13.69%). Efforts should be made to encourage the vaccine in this vulnerable population to protect them from the health risks of the COVID-19 virus.
Key Points
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COVID-19 vaccine acceptance rates in our population were 13.6%.
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Accepting Tdap and influenza vaccines increased the likelihood of accepting the COVID vaccine.
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Pregnant patients with respiratory illnesses were more likely to decline the COVID vaccine.
Publication History
Received: 07 October 2021
Accepted: 11 August 2022
Article published online:
19 October 2022
© 2022. Thieme. All rights reserved.
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References
- 1 “CDC COVID Data Tracker.” Centers for Disease Control and Prevention, Centers for Disease Control and Prevention, June 2021. Accessed September 2, 2022 at: covid.cdc.gov/covid-data-tracker/#vaccinations
- 2 “CDC COVID Data Tracker.” Centers for Disease Control and Prevention, Centers for Disease Control and Prevention, 21 June 2021. Accessed September 2, 2022 at: covid.cdc.gov/covid-data-tracker/
- 3 Mohamadian M, Chiti H, Shoghli A, Biglari S, Parsamanesh N, Esmaeilzadeh A. COVID-19: virology, biology and novel laboratory diagnosis. J Gene Med 2021; 23 (02) e3303
- 4 Wastnedge EAN, Reynolds RM, van Boeckel SR. et al. Pregnancy and COVID-19. Physiol Rev 2021; 101 (01) 303-318
- 5 Allotey J, Stallings E, Bonet M. et al; for PregCOV-19 Living Systematic Review Consortium. Clinical manifestations, risk factors, and maternal and perinatal outcomes of coronavirus disease 2019 in pregnancy: living systematic review and meta-analysis. BMJ 2020; 370: m3320
- 6 Panagiotakopoulos L, Myers TR, Gee J. et al. SARS-CoV-2 infection among hospitalized pregnant women: reasons for admission and pregnancy characteristics—eight US health care centers, March 1–May 30, 2020. MMWR Morb Mortal Wkly Rep 2020; 69 (38) 1355-1359
- 7 Di Mascio D, Khalil A, Saccone G. et al. Outcome of coronavirus spectrum infections (SARS, MERS, COVID-19) during pregnancy: a systematic review and meta-analysis. Am J Obstet Gynecol MFM 2020; 2 (02) 100107
- 8 Quinn SC, Jamison A, Freimuth VS, An J, Hancock GR, Musa D. Exploring racial influences on flu vaccine attitudes and behavior: results of a national survey of White and African American adults. Vaccine 2017; 35 (08) 1167-1174
- 9 DiTosto JD, Weiss RE, Yee LM, Badreldin N. Association of Tdap vaccine guidelines with vaccine uptake during pregnancy. PLoS One 2021; 16 (07) e0254863
- 10 Williams WW, Lu PJ, O'Halloran A. et al. Surveillance of vaccination coverage among adult populations - United States, 2015. MMWR Surveill Summ 2017; 66 (11, No. SS-11): 1-28
- 11 Razzaghi H, Meghani M, Pingali C. et al. COVID-19 vaccination coverage among pregnant women during pregnancy - eight integrated health care organizations, United States, December 14, 2020-May 8, 2021. MMWR Morb Mortal Wkly Rep 2021; 70 (24) 895-899 DOI
- 12 Ayhan SG, Oluklu D, Atalay A. et al. COVID-19 vaccine acceptance in pregnant women. Int J Gynaecol Obstet 2021; 154 (02) 291-296
- 13 Skjefte M, Ngirbabul M, Akeju O. et al. COVID-19 vaccine acceptance among pregnant women and mothers of young children: results of a survey in 16 countries. Eur J Epidemiol 2021; 36 (02) 197-211
- 14 Sallam M. COVID-19 vaccine hesitancy worldwide: a concise systematic review of vaccine acceptance rates. Vaccines (Basel) 2021; 9 (02) 160
- 15 Larson HJ, Jarrett C, Eckersberger E, Smith DMD, Paterson P. Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: a systematic review of published literature, 2007-2012. Vaccine 2014; 32 (19) 2150-2159
- 16 ACOG and SMFM recommend COVID-19 vaccination for pregnant individuals. ACOG. (2021, July 30). Retrieved June 9, 2022. Accessed September 2, 2022 at: https://www.acog.org/news/news-releases/2021/07/acog-smfm-recommend-covid-19-vaccination-for-pregnant-individuals
- 17 Wales DP, Khan S, Suresh D, Ata A, Morris B. Factors associated with Tdap vaccination receipt during pregnancy: a cross-sectional study. Public Health 2020; 179: 38-44
- 18 Qiu X, Bailey H, Thorne C. Barriers and facilitators associated with vaccine acceptance and uptake among pregnant women in high income countries: a mini-review. Front Immunol 2021; 12: 626717
- 19 Kilich E, Dada S, Francis MR. et al. Factors that influence vaccination decision-making among pregnant women: a systematic review and meta-analysis. PLoS One 2020; 15 (07) e0234827
- 20 Ricotta EE, Kwan JL, Smith BA, Evans NG. Chronic diseases: perceptions about Covid-19 risk and vaccination. medRxiv 2021; (e-pub ahead of print)
- 21 Huang BZ, Chen Z, Sidell MA. et al. Asthma disease status, COPD, and COVID-19 severity in a large multiethnic population. J Allergy Clin Immunol Pract 2021; 9 (10) 3621-3628.e2