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Synthesis 2001(5): 0731-0734
DOI: 10.1055/s-2001-12760
PAPER
© Georg Thieme Verlag Stuttgart · New York

Preparation of 1,3-Selenazol-4-one Derivatives from Primary Selenoamides and Haloacyl Halides

Mamoru Koketsu*, Yuichi Takenaka, Hideharu Ishihara*
Department of Chemistry, Faculty of Engineering, Gifu University, Gifu 501-1193, Japan
Fax: +81(58)2301893; e-Mail: koketsu@cc.gifu-u.ac.jp;
Further Information

Publication History

Received 8 December 2000
Publication Date:
15 October 2004 (online)

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Abstract

1,3-Selenazol-4-one derivatives were synthesized by the reaction of primary selenoamides with haloacyl halides in the presence of pyridine.

Key words

primary selenoamide - haloacyl halide - pyridine - 1,3-selenazol-4-one - heterocycles

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4

Reactions of 1a and 2a at -20 °C, 0 °C, r. t. and reflux gave 3a in 69, 80, 77 and 74% yields, respectively.