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Am J Perinatol 2002; 19(6): 297-302
DOI: 10.1055/s-2002-34468
Copyright © 2002 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Akinesia, Arthrogryposis, Craniosynostosis: A Presentation of Neonatal Myasthenia with Fetal Onset

Sylvain Cantagrel1 , Laure Maury1 , Anne-Marie Yamamoto2 , Josette Maheut3 , Annick Toutain4 , Pierre Castelnau3
  • 1Pediatric and Neonatal Intensive Care Unit, Clocheville Children's Hospital, Tours, France
  • 2Immunology Laboratory, Necker Children's Hospital, Paris, France
  • 3Pediatric Neurology Unit, Clocheville Children's Hospital, Tours, France
  • 4Genetic Unit, Bretonneau Hospital,Tours, France
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Publication History

Publication Date:
01 October 2002 (online)

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ABSTRACT

Major akinesia with arthrogryposis and craniosynostosis at birth mimics irreversible disorders of the nervous system of pejorative outcome. In this context, the early detection of anti-acetylcholine fetal receptor antibodies in the mother may allow rapid diagnosis of transient neonatal myasthenia of favorable prognosis.

KEYWORDS

Arthrogryposis - craniosynostosis - fetal - myasthenia

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