Nuklearmedizinische Diagnostik des primären Hyperparathyreoidismus (pHPT)

Zusammenfassung

Die nuklearmedizinische Nebenschilddrüsendiagnostik hat in jüngerer Vergangenheit zunehmende Bedeutung erlangt. Durch die Einführung minimal invasiver Operationstechniken ist eine präoperative Bildgebung für die Planung des Eingriffs Voraussetzung. Die Sestamibi-Szintigraphie hat in diesem Zusammenhang in zahlreichen Studien eine Überlegenheit gegenüber anderen Verfahren im Hinblick auf die Sensitivität bei der Detektion von Läsionen, insbesondere beim primären Hyperparathyreoidismus, gezeigt. Demzufolge wird dieses Untersuchungsverfahren nicht nur wie bisher vor Rezidiveingriffen oder bei persistierender Erkrankung, sondern auch erfolgreich vor Erstoperationen eingesetzt. Die vermehrte Nutzung der SPECT-Technik konnte in den letzten Jahren zu einer weiteren Steigerung der Detektionsrate beitragen und sollte großzügig Verwendung finden.

Abstract

Nuclear medicine recently has gained importance in the diagnosis of primary hyperparathyroidism. Stimulated by the introduction of minimal invasive surgery preoperative imaging is mandatory for the planning of the surgical approach. Sestamibi scintigraphy has proven its superiority in sensitivity concerning the lesion detection especially in primary hyperparathyroidism as compared to other imaging modalities. Therefore this test is not only used for the diagnosis of relapsing or persistent disease but also successfully implemented in the initial work-up. The wider use of SPECT contributed significantly to a further increase of the detection rate and is recommended as a standard procedure.

Schlüsselwörter

Primärer Hyperparathyreoidismus - Sestamibi - Szintigraphie - SPECT

Key words

Primary hyperparathyroidism - Sestamibi - Scintigraphy - SPECT

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