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Semin Thromb Hemost 2010; 36(7): 685-692
DOI: 10.1055/s-0030-1265830
EDITORIAL

© Thieme Medical Publishers

Winners of the 2010 Eberhard F. Mammen Award for Most Popular Article during 2008–2009

Emmanuel J. Favaloro1
  • 1Department of Haematology, Institute of Clinical Pathology and Medical Research (ICPMR), Westmead Hospital, SWAHS, Westmead, NSW, Australia
Further Information

Publication History

Publication Date:
26 October 2010 (online)

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As we have mentioned on several occasions,[1] [2] [3] Thieme, the publisher of Seminars in Thrombosis and Hemostasis, recently created the Eberhard F. Mammen Excellence in Thrombosis and Hemostasis Awards in honor of Eberhard Mammen (Fig. [1]) and in recognition of his contribution to this field and to the journal he both founded and steered for over three decades. These awards began in 2009 with these two categories:

Figure 1 Eberhard F. Mammen (1930–2008).

Most popular article awards: Awarded to the authors of the most popular articles published in Seminars in Thrombosis and Hemostasis. The awards are determined by the editor in chief on the basis of user statistics from Thieme eJournals from the preceding 2 years. The awards consist of two major cash prizes of US $1000 plus open access status for these articles thereafter. Young investigator awards: Best presentation or meeting abstract by a young investigator, as presented or delivered to an international meeting on a topic related to the fields of thrombosis and hemostasis and whose subject matter is determined to be in the spirit of Dr. Mammen. Up to six cash prizes of US $1,000 in any year are awarded for one or more presentations at each of three or more international meetings per year. The recipients prepare a review or other related article on the topic of their presentation for publication in Seminars in Thrombosis and Hemostasis.

Further details of the awards and the award winners are posted online at http://www.thieme.com/sth, and previous award winner announcements are also available in print.[4] [5]

It is with great pleasure that we announce the winners of the 2010 Eberhard F. Mammen award for the most popular articles from Seminars in Thrombosis and Hemostasis for the period of 2008–2009 inclusive. The top 50 downloaded articles[6] [7] [8] [9] [10] [11] [12] [13] [14] [15] [16] [17] [18] [19] [20] [21] [22] [23] [24] [25] [26] [27] [28] [29] [30] [31] [32] [33] [34] [35] [36] [37] [38] [39] [40] [41] [42] [43] [44] [45] [46] [47] [48] [49] [50] [51] [52] [53] [54] [55] from this period are also identified in Table [1].

Table 1 Top 50 Downloaded Articles from Seminars in Thrombosis and Hemostasis (2008–2009) Rank Article 1. Harenberg J, Wehling M. Current and future prospects for anticoagulant therapy: inhibitors of factor Xa and factor IIa. Semin Thromb Hemost 2008;34(1):39–57 2. Prechel M, Walenga JM. The laboratory diagnosis and clinical management of patients with heparin-induced thrombocytopenia: an update. Semin Thromb Hemost 2008;34(1):86–96 3. Fareed J, Hoppensteadt DA, Fareed D, et al. Survival of heparins, oral anticoagulants, and aspirin after the year 2010. Semin Thromb Hemost 2008;34(1):58–73 4. Asherson RA, Cervera R, Merrill JT, Erkan D. Antiphospholipid antibodies and the antiphospholipid syndrome: clinical significance and treatment. Semin Thromb Hemost 2008;34(3):256–266 5. Jurk K, Kehrel BE. Platelets: physiology and biochemistry. Semin Thromb Hemost 2005;31(4):381–392 6. Wong RC, Favaloro EJ. Clinical features, diagnosis, and management of the antiphospholipid syndrome. Semin Thromb Hemost 2008;34(3):295–304 7. Enjeti AK, Lincz LF, Seldon M. Detection and measurement of microparticles: an evolving research tool for vascular biology. Semin Thromb Hemost 2007;33(8):771–779 8. Tincani A, Bazzani C, Zingarelli S, Lojacono A. Lupus and the antiphospholipid syndrome in pregnancy and obstetrics: clinical characteristics, diagnosis, pathogenesis, and treatment. Semin Thromb Hemost 2008;34(3):267–273 9. Viiala NO, Larsen SR, Rasko JE. Gene therapy for hemophilia: clinical trials and technical tribulations. Semin Thromb Hemost 2009;35(1):81–92 10. Pierangeli SS, Chen PP, Raschi E, et al. Antiphospholipid antibodies and the antiphospholipid syndrome: pathogenic mechanisms. Semin Thromb Hemost 2008;34(3):236–250 11. Tripodi A, van den Besselaar A. Laboratory monitoring of anticoagulation: where do we stand? Semin Thromb Hemost 2009;35(1):34–41 12. Sobieraj-Teague M, O'Donnell M, Eikelboom J. New anticoagulants for atrial fibrillation. Semin Thromb Hemost 2009;35(5):515–524 13. Lippi G, Favaloro EJ, Franchini M, Guidi GC. Milestones and perspectives in coagulation and hemostasis. Semin Thromb Hemost 2009;35(1):9–22 14. Tiu RV, Mountantonakis SE, Dunbar AJ, Schreiber MJ Jr. Tumor lysis syndrome. Semin Thromb Hemost 2007;33(4):397–407 15. Watson HG, Greaves M. Can we predict bleeding? Semin Thromb Hemost 2008;34(1):97–103 16. Hunt BJ. Pediatric antiphospholipid antibodies and antiphospholipid syndrome. Semin Thromb Hemost 2008;34(3):274–281 17. Laux V, Perzborn E, Kubitza D, Misselwitz F. Preclinical and clinical characteristics of rivaroxaban: a novel, oral, direct factor Xa inhibitor. Semin Thromb Hemost 2007;33(5):515–523 18. Blum W, Porcu P. Therapeutic apheresis in hyperleukocytosis and hyperviscosity syndrome. Semin Thromb Hemost 2007;33(4):350–354 19. Boekholdt SM, Kramer MH. Arterial thrombosis and the role of thrombophilia. Semin Thromb Hemost 2007;33(6):588–596 20. Franchini M, Franchi M, Bergamini V, Salvagno GL, Montagnana M, Lippi G. A critical review on the use of recombinant factor VIIa in life-threatening obstetric postpartum hemorrhage. Semin Thromb Hemost 2008;34(1):104–112 21. Levi M, Löwenberg EC. Thrombocytopenia in critically ill patients. Semin Thromb Hemost 2008;34(5):417–424 22. Cohn DM, Roshani S, Middeldorp S. Thrombophilia and venous thromboembolism: implications for testing. Semin Thromb Hemost 2007;33(6):573–581 23. Wada H, Usui M, Sakuragawa N. Hemostatic abnormalities and liver diseases. Semin Thromb Hemost 2008;34(8):772–778 24. Jeske WP, Walenga JM, Hoppensteadt DA, et al. Differentiating low-molecular-weight heparins based on chemical, biological, and pharmacologic properties: implications for the development of generic versions of low-molecular-weight heparins. Semin Thromb Hemost 2008;34(1):74–85 25. Ho VT, Linden E, Revta C, Richardson PG. Hepatic veno-occlusive disease after hematopoietic stem cell transplantation: review and update on the use of defibrotide. Semin Thromb Hemost 2007;33(4):373–388 26. Galli M. Clinical utility of laboratory tests used to identify antiphospholipid antibodies and to diagnose the antiphospholipid syndrome. Semin Thromb Hemost 2008;34(4):329–334 27. Favaloro EJ. Clinical utility of the PFA-100. Semin Thromb Hemost 2008;34(8):709–733 28. Bernardi E, Pesavento R, Prandoni P. Upper extremity deep venous thrombosis. Semin Thromb Hemost 2006;32(7):729–736 29. Selleng K, Selleng S, Greinacher A. Heparin-induced thrombocytopenia in intensive care patients. Semin Thromb Hemost 2008;34(5):425–438 30. Harenberg J. Development of new anticoagulants: present and future. Semin Thromb Hemost 2008;34(8):779–793 31. Mariani G, Bernardi F. Factor VII Deficiency. Semin Thromb Hemost 2009;35(4):400–406 32. Gisondi P, Girolomoni G. Psoriasis and atherothrombotic diseases: disease-specific and non-disease-specific risk factors. Semin Thromb Hemost 2009;35(3):313–324 33. Esmon CT. Inflammation and the activated protein C anticoagulant pathway. Semin Thromb Hemost 2006;32(Suppl 1):49–60 34. Schaffner F, Ruf W. Tissue factor and protease-activated receptor signaling in cancer. Semin Thromb Hemost 2008;34(2):147–153 35. Roberts HR, Hoffman M, Monroe DM. A cell-based model of thrombin generation. Semin Thromb Hemost. 2006;32 (Suppl) 1:32-8. 36. Harris EN, Pierangeli SS. Primary, secondary, and catastrophic antiphospholipid syndrome: what's in a name? Semin Thromb Hemost 2008;34(3):219–226 37. Wong RC, Favaloro EJ. Antiphospholipid antibodies and the antiphospholipid syndrome. I: pathogenesis, clinical features, diagnosis, and management. Preface. Semin Thromb Hemost 2008;34(3):213–218 38. Douma RA, Kamphuisen PW. Thrombolysis for pulmonary embolism and venous thrombosis: is it worthwhile? Semin Thromb Hemost 2007;33(8):821–828 39. Lippi G, Franchini M, Montagnana M, Guidi GC. Coagulation testing in pediatric patients: the young are not just miniature adults. Semin Thromb Hemost 2007;33(8):816–820 40. McGlasson DL, Fritsma GA. Whole blood platelet aggregometry and platelet function testing. Semin Thromb Hemost 2009;35(2):168–180 41. Zakarija A, Bennett C. Drug-induced thrombotic microangiopathy. Semin Thromb Hemost 2005;31(6):681–690 42. Espinosa G, Bucciarelli S, Asherson RA, Cervera R. Morbidity and mortality in the catastrophic antiphospholipid syndrome: pathophysiology, causes of death, and prognostic factors. Semin Thromb Hemost 2008;34(3):290–294 43. Miesbach W. Neurologic symptoms as a feature of the antiphospholipid syndrome. Semin Thromb Hemost 2008;34(3):286–289 44. Girolami B, Girolami A. Heparin-induced thrombocytopenia: a review. Semin Thromb Hemost 2006;32(8):803–809 45. Althaus K, Greinacher A. MYH9-related platelet disorders. Semin Thromb Hemost 2009;35(2):189–203 46. Favaloro EJ, Wong RC. Laboratory testing and identification of antiphospholipid antibodies and the antiphospholipid syndrome: a potpourri of problems, a compilation of possible solutions. Semin Thromb Hemost 2008;34(4):389–410 47. Savi P, Herbert JM. Clopidogrel and ticlopidine: P2Y12 adenosine diphosphate-receptor antagonists for the prevention of atherothrombosis. Semin Thromb Hemost 2005;31(2):174–183 48. Dempfle CE, Borggrefe M. Point of care coagulation tests in critically ill patients. Semin Thromb Hemost 2008;34(5):445–450 49. Kenet G, Strauss T, Kaplinsky C, Paret G. Hemostasis and thrombosis in critically ill children. Semin Thromb Hemost 2008;34(5):451–458 50. Harrison P, Mumford A. Screening tests of platelet function: update on their appropriate uses for diagnostic testing. Semin Thromb Hemost 2009;35(2):150–157

The two most popular articles were by Job Harenberg and Martin Wehling (Fig. [2]), Current and Future Prospects for Anticoagulant Therapy: Inhibitors of Factor Xa and Factor IIa,[6] and Margaret Prechel and Jeanine Walenga (Fig. [3]), The Laboratory Diagnosis and Clinical Management of Patients with Heparin-Induced Thrombocytopenia: An Update.[7] Also for this year, given the close proximity of the second- and third-rank position, we decided to grant a third prize, to Jawed Fareed and colleagues (Fig. [4]), Survival of Heparins, Oral Anticoagulants, and Aspirin after the Year 2010.[8] We accordingly offer our sincerest congratulations to these 2010 Eberhard F. Mammen award recipients. I was very pleased to see these three articles awarded this honor, and not just because I was the guest editor for the issue in which they appeared (all three came from the same issue, one of our Hot Topic issues from 2008).

Figure 2 Martin Wehling (left) and Job Harenberg (right). Photo taken at an angiology symposium in Kitzbühel, Austria.

Figure 3 Margaret Prechel (left) and Jeanine Walenga (right). Photo taken at the Cardiovascular Institute, Loyola University Medical Center, Maywood, Illinois, USA.

Figure 4 Jawed Fareed (left) and Debra Hoppensteadt (right). Photo taken at the Loyola University Medical Center, Maywood, Illinois, USA, in a conference room where these researchers teach students.

Job Harenberg and Martin Wehling deserve to win one of these awards for many reasons in addition to the preceding explanation related to highest downloads. Job Harenberg, the corresponding author for this article and an old friend of Eberhard Mammen, was very pleased to hear of his award. He is also a longtime supporter of this journal. Dr. Harenberg has been a contributing author to 34 articles in Seminars in Thrombosis and Hemostasis dating back to 1989, including one other article listed in the latest top 50 (Table [1]), the topic of which was also related to anticoagulants. He has worked in the Thrombosis and Haemostasis Unit of the Department of Internal Medicine and is currently a professor in the Department of Clinical Pharmacology at the Faculty of Medicine Mannheim of the University of Heidelberg, Mannheim, Germany. His main area of research is the development and evaluation of tests for the diagnosis of thrombotic diseases and the clinical and laboratory evaluation of new anticoagulant drugs to treat venous and arterial thromboembolic diseases. Dr. Wehling is a specialist in cardiology and has a special interest in the treatment of cardiovascular diseases. He is currently head of the Department of Clinical Pharmacology at the Faculty of Medicine Mannheim. Both authors have been collaborating for > 2 years in the field of clinical and pharmacological research into thromboembolic diseases.

The popularity of the article by Margaret Prechel and Jeanine Walenga on heparin-induced thrombocytopenia was not surprising to me, given that the same topic was discussed by one of the award winners from 2009.[4] [49] Nevertheless, the current winning authors also well deserve this award. Dr. Walenga also was an old friend of Eberhard Mammen and a longtime supporter of this journal. She was a contributing author to a staggering 83 articles in Seminars in Thrombosis and Hemostasis dating back to 1982, including one other one listed in the latest top 50 that was also related to anticoagulants. Currently, Drs. Walenga and Prechel are faculty members with joint appointments in the Departments of Thoracic and Cardiovascular Surgery and Pathology at the Loyola University Medical Center in Maywood, Illinois, USA. Their main area of focus is heparin-induced thrombocytopenia (HIT). They direct a reference clinical laboratory that performs assays for HIT antibodies, and they carry out research on the pathological mechanisms of HIT, improvement of clinical laboratory assays for HIT, and alternative anticoagulants for this patient population.

Jawed Fareed, yet another friend of Dr. Mammen and supporter of the journal, also wins an award with several colleagues for their article on anticoagulants. Jawed has been a contributing author to an even more impressive 115 articles in Seminars in Thrombosis and Hemostasis, also dating back to 1982, including one other article listed in the latest top 50. Indeed, Drs. Fareed and Walenga are longtime collaborators. Not only do they share co-authorship on one of the articles listed on the latest top 50 list (Table [1]), they also shared authorships on 71 articles in Seminars in Thrombosis and Hemostasis dating back to 1982. Dr. Fareed is greatly honored to be receiving this award and considered Dr. Mammen a mentor and great friend. Dr. Fareed and one of his coauthors, Dr. Hoppensteadt, have worked in the Hemostasis and Thrombosis Research Unit, and they are currently professors in the Departments of Pathology and Pharmacology at the Loyola University Medical Center. Their main area of research is the development of newer tests for the diagnosis of thrombosis and the objective elevation of newer drugs to treat thrombosis and cardiovascular disease.

A special note of thanks is due to Job Harenberg, Jeanine Walenga and Jawed Fareed for their contributions over the years, and congratulations again to the Eberhard F. Mammen most popular article award winners of 2010.

The remaining 47 chapters listed in Table [1] relate to a variety of topics in the field of thrombosis and hemostasis. Of some interest is that the earlier chapter on heparin-induced thrombocytopenia mentioned earlier, by the father and son team of Girolami and Girolami, was again listed in the latest top 50 listing of 2010 (Table [1]), as was the other award-winning article of 2009, by Jurk and Kehrel,[4] [10] Platelets: Physiology and Biochemistry, coming in at number 5 in the last 2010 list. This is an amazing achievement. Published in 2005, this popular article was also featured on the top 20 most popular article listings in 2005, 2006, and 2007.[56] The article by Girolami and Girolami[4] was published in late 2006 and was also the most popular article of 2007.[56]

What were the generally popular topics of 2008 and 2009, the basis of the listing in Table [1]? There was another article on heparin-induced thrombocytopenia, this time related to the setting of intensive care.[34] As already noted, several other articles dealt with the topic of current or emerging anticoagulants or their monitoring.[16] [17] [22] [29] There were also several articles on the perennial favorite, thrombophilia, or thrombosis in its myriad incantations.[27] [33] [37] Of some personal interest to me was the popularity of several articles from two issues we ran on the antiphospholipid (antibody) syndrome (APS) in 2008, with 11 of these making the top 50 listing (Table [1])[9] [11] [13] [15] [21] [31] [41] [42] [47] [48] [51] and four making the top 10. Among these was an article by Ron Asherson,[11] which deserves a special mention as he sadly passed away just before the issue's publication.[57] Also deserving of a special mention and proving popular among the readership of Seminars in Thrombosis and Hemostasis were the articles written with the assistance of Richard Wong, my co-guest editor for those two issues on APS.[11] [41] [51] Finally, on the topic of APS, a special thank you to Nigel Harris and Silvia Pierangeli for their many contributions to these two issues, two articles of which made the top 50 listing (Table [1]).[15] [41]

Finally, I wish to acknowledge the contributions made by all of the other authors listed in Table [1]. Your work has managed to capture that extra level of attention from your scientific and clinical colleagues. Although I do not want to detract from any contributions that I have not mentioned here, I must extend a special note of gratitude to Giuseppe Lippi and Massimo Franchini, relatively new friends of Seminars in Thrombosis and Hemostasis. They each succeeded in getting three articles on the 50 most popular list (Table [1]), and they are always willing to provide valuable contributions to our journal. For those contributors to Seminars in Thrombosis and Hemostasis who did not make the top 50 list, please be assured that your work has made a very important contribution to the journal. We are all very grateful for your participation in Seminars in Thrombosis and Hemostasis.

I look forward to seeing the next listing in 2011!

REFERENCES

Emmanuel J FavaloroPh.D. M.A.I.M.S. 

Department of Haematology, Institute of Clinical Pathology and Medical Research (ICPMR)

Westmead Hospital, WSAHS, Westmead, NSW 2145, Australia

Email: emmanuel.favaloro@swahs.health.nsw.gov.au