A Novel System for the Synthesis of 2-Aminobenzthiazoles using Sodium Dichloroiodate

Abstract

2-Aminobenzthiazole is a privileged scaffold with a range of biological activities. However, to date, an efficient protocol for the synthesis of this ring system using aniline as a starting material has been lacking. Herein, for the first time, we describe a highly efficient and mild protocol for the synthesis of 2-aminiobenzthiazole using NaICl₂.

Key words

synthetic methods - oxidative cyclization - sodium dichloroiodate - aniline - aminobenzthiazole

• References and Notes

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