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Endosc Int Open 2016; 04(11): E1223-E1226
DOI: 10.1055/s-0042-110096
Case report
© Georg Thieme Verlag KG Stuttgart · New York

Endoscopic ultrasound in the diagnosis of acinar cell carcinoma of the pancreas: contrast-enhanced endoscopic ultrasound, endoscopic ultrasound elastography, and pathological correlation

Tanyaporn Chantarojanasiri
1   Nagoya University Graduate School of Medicine – Department of Gastroenterology and Hepatology, Nagoya, Japan
2   Police General Hospital, Department of Internal Medicine, Bangkok, Thailand
,
Yoshiki Hirooka
3   Nagoya University Hospital – Department of Endoscopy, Nagoya, Japan
,
Hiroki Kawashima
1   Nagoya University Graduate School of Medicine – Department of Gastroenterology and Hepatology, Nagoya, Japan
,
Eizaburo Ohno
3   Nagoya University Hospital – Department of Endoscopy, Nagoya, Japan
,
Takeshi Yamamura
1   Nagoya University Graduate School of Medicine – Department of Gastroenterology and Hepatology, Nagoya, Japan
,
Kohei Funasaka
3   Nagoya University Hospital – Department of Endoscopy, Nagoya, Japan
,
Masanao Nakamura
4   Nagoya University Graduate School of Medicine – Division of Therapeutic Medicine, Department of Internal Medicine, Nagoya, Japan
,
Ryoji Miyahara
5   Nagoya University Graduate School of Medicine – Department of Gastroenterology, Nagoya, Japan
,
Masatoshi Ishigami
1   Nagoya University Graduate School of Medicine – Department of Gastroenterology and Hepatology, Nagoya, Japan
,
Osamu Watanabe
5   Nagoya University Graduate School of Medicine – Department of Gastroenterology, Nagoya, Japan
,
Masato Nakaguro
6   Nagoya University Graduate School of Medicine – Department of Pathology and Clinical Laboratories, Nagoya, Japan
,
Yoshie Shimoyama
7   Nagoya University Hospital – Department of Pathology and Clinical Laboratories, Nagoya, Japan
,
Shigeo Nakamura
7   Nagoya University Hospital – Department of Pathology and Clinical Laboratories, Nagoya, Japan
,
Hidemi Goto
5   Nagoya University Graduate School of Medicine – Department of Gastroenterology, Nagoya, Japan
› Author Affiliations
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Publication History

submitted08 March 2016

accepted after revision17 May 2016

Publication Date:
10 November 2016 (online)

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We report a case series of five patients with pancreatic acinar cell carcinoma who received surgical treatment and compared the preoperative contrast-enhanced endoscopic ultrasound (EUS) and EUS elastography patterns with the surgical specimens. The contrast-enhanced EUS indicated vascular tumors with gradual enhancement in four patients and a hypovascular tumor in one patient. The elastography indicated an elastic score of 3 (hard lesion with softer border) in two patients and a score of 5 (hard lesion, which included the surrounding area) in two patients. In tumors with an elastic score of 5, the pathology exhibited abundant hyalinizing fibrous stroma or massive tumor invasion to the surrounding tissue. We concluded that acinar cell carcinoma of the pancreas has various patterns of EUS contrast-enhancement and elastography, depending on the pathologic phenotype.

 

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