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Synlett 1993; 1993(2): 135-136
DOI: 10.1055/s-1993-22377
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Reduction of Nitro Compounds with Borohydride Exchange Resin - Nickel Acetate

Nung Min Yoon* , Jaesung Choi
  • *Department of Chemistry, Sogang University, Seoul 121-742, Republic of Korea
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Publication History

Publication Date:
19 March 2002 (online)

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Borohydride Exchange Resin (BER) - nickel acetate system readily reduces both aliphatic and aromatic nitro compounds to the corresponding amino compounds in excellent yields in methanol. This system tolerates hydroxymethyl, phenol, methoxy, acetal, acetyl, carboxylic acid, ester, cyano and halogen (Cl and Br) substituents on the benzene ring.