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Synthesis 1993; 1993(2): 250-262
DOI: 10.1055/s-1993-25842
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Asymmetric Addition to Chiral Aromatic and Unsaturated Oxazolines Using a Novel Chiral Auxiliary

A. I. Meyers* , Wolfgang Schmidt, Marc J. Mckennon
  • *Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, USA
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Publication Date:
17 September 2002 (online)

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By utilizing S-serine, both enantiomers of the reduced methoxyamino alcohol (12) were efficiently prepared. The corresponding oxazolines, prepared from these auxiliaries, showed favorable properties toward additions to naphthalenes 22 and cyclohexene, 27.