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Ultraschall Med 2007; 28(1): 40-44
DOI: 10.1055/s-2006-926716
Original Article

© Georg Thieme Verlag KG Stuttgart · New York

3D Power Doppler Analysis of the Vascularisation in Tumours of the Oral Cavity

3D-Power-Doppler-Analyse der Vaskularisation von Tumoren des MundraumsJ. Rebol1 , B. Brkljačić2 , Ž. Bumber3 , S. Pšeničnik4 , P. Povalej5
  • 1Department of Otorhinolaryngology and Cervicofacial Surgery, Maribor Teaching Hospital, Slovenia
  • 2Department of Radiology, University Hospital Dubrava, Zagreb, Croatia
  • 3Department of Otorhinolaryngology, ORL Clinic Šalata, Zagreb, Croatia
  • 4Department of Biomedical Technics, Maribor Teaching Hospital, Slovenia
  • 5Faculty of Computer Science and Engineering, University of Maribor
Further Information

Publication History

received: 1.8.2005

accepted: 16.3.2006

Publication Date:
15 May 2006 (online)

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Zusammenfassung

Ziel: Die Studie hatte zum Ziel, mithilfe von dreidimensionaler (3D-)Power-Doppler-Sonografie Tumorvolumen und Vaskularisation bei Patienten mit Tumoren des Mundraums zu bestimmen. Material und Methoden: Die 3D-Power-Doppler-Untersuchung wurde bei 49 Patienten mit Tumoren des Mundraums präoperativ durchgeführt. Digital gespeicherte Daten wurden durch eine 3D-View-Programmsoftware analysiert, die unter anderem das „VOCAL-Imaging-Programm” beinhaltet. Durch die Anwendung von VOCAL können die Ränder einer Struktur (Tumor) identifiziert und ihr Volumen bestimmt werden. Die Vaskularisation des Tumors wurde mithilfe von dreidimensionalen farbigen Histogrammen analysiert und dann die Vaskularisationsindizes bestimmt. Ergebnisse: Vaskularisationsindizes VI und VFI waren bei Patienten mit Metastasen im Halsbereich signifikant höher. Die Unterschiede zwischen den Vaskularisationsindizes bei dem N+- und N0-Hals waren statistisch signifikant (p < 0,05). Die Flussindex-Werte (FI) waren zwischen N+- und N0-Hals statistisch nicht signifikant. Schlussfolgerung: Volumen und Vaskularisation von Tumoren im Mundraum konnten durch 3D-Power-Doppler-Ultraschall erfolgreich untersucht werden. Die Tumorvaskularisation ist ausgeprägter bei metastasierenden als bei nicht metastasierenden Tumoren.

Abstract

Purpose: The aim of this study was to determine the volume and vascularisation of tumours by three-dimensional (3D) power Doppler ultrasound in patients with “tumours of the oral cavity”. Materials and Methods: Three-dimensional (3D) power Doppler ultrasound investigation was performed pre-operatively on 49 patients with carcinomas of the oral cavity. Digitally-stored data were analysed with 3D View program software, a part of which is the “VOCAL-Imaging program”. By using VOCAL, the borders of a structure (tumour) can be determined and its volume calculated. The vascularisation of the tumour was determined by analysing three-dimensional colour histograms, and the vascularisation indices were calculated. Results: Vascularisation indices VI and VFI were significantly higher in patients with neck metastases. The differences between the vascularisation indices in N+ and N0 necks were statistically significant (p < 0.05). The flow index (FI) values between N+ and N0 necks were not statistically different. Conclusion: The volume and vascularisation of tumours of the oral cavity could be determined effectively by three-dimensional power Doppler ultrasound. Tumour vascularisation is higher in metastatic than in non-metastatic tumours.

Schlüsselwörter

Dreidimensionale Sonografie - dreidimensionaler Power-Doppler - Tumoren des Mundraums - Vaskularisation - Metastasen im Halsbereich

Key words

Three-dimensional ultrasonography - three-dimensional power Doppler - tumours of the oral cavity - vascularisation - neck metastases

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Janez  Rebol, MD MSc

Department of Otorhinolaryngology and Cervicofacial Surgery, Maribor University Hospital

Ljubljanska 5

2000 Maribor

Slovenia

Phone: ++38/6 23/21 15 92

Fax: ++38/6 23/31 23 93

Email: janez.rebol@guest.arnes.si