Four New Chalcones from Erythrina abyssinica

Abstract

Four new chalcones 1 - 4, named abyssinones A - D, were isolated from the stem bark of the plant Erythrina abyssinica and their structures were elucidated on the basis of spectroscopic analyses. The compounds 1, 3, and 4 were found to exhibit moderate cytotoxic activity against the human colorectal cancer cell line (Caco2) with IC₅₀ values of 13.3, 15.1, and 11.1 μM, respectively.

Key words

Erythrina abyssinica - Leguminosae - chalcones - cytotoxic activity

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