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CC BY-NC-ND 4.0 · Arq Neuropsiquiatr 2017; 75(01): 69-71
DOI: 10.1590/0004-282X20160166
Historical Notes

Wilson's disease: the 60th anniversary of Walshe's article on treatment with penicillamine

Doença de Wilson: o 60° aniversário do artigo de Walshe no tratamento com penicilamina
Hélio A. G. Teive
1   Universidade Federal do Paraná, Hospital de Clínicas, Serviço de Neurologia, Unidade de Distúrbios dos Movimentos, Curitiba PR, Brasil
,
Egberto Reis Barbosa
2   Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Departamento de Neurologia, São Paulo SP, Brasil
,
Andrew J. Lees
3   UCL Institute of Neurology, Reta Lila Weston Institute for Neurological Studies, Department of Molecular Neuroscience, London, UK
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ABSTRACT

This historical review describes Professor Walshe's seminal contribution to the treatment of Wilson's disease on the 60th anniversary of his pioneering article on penicillamine, the first effective treatment for the condition.

RESUMO

Esta revisão histórica enfatiza a contribuição seminal do Professor Walshe no tratamento da doença de Wilson (DW), com o seu trabalho pioneiro sobre o uso de penicilamina, o primeiro tratamento efetivo do mundo, publicado 60 anos atrás.

Keywords:

hepatolenticular degeneration - therapeutics - penicillamine

Palavras-chave:

degeneração hepatolenticular - terapêutica - penicilamina


Publication History

Received: 15 May 2016

Accepted: 28 September 2016

Article published online:
06 September 2023

© 2023. Academia Brasileira de Neurologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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