CC BY-NC-ND 4.0 · Endosc Int Open 2018; 06(09): E1126-E1129
DOI: 10.1055/a-0599-6008
Case report
Owner and Copyright © Georg Thieme Verlag KG 2018

Salvage endoscopic resection in patients with esophageal adenocarcinoma after chemoradiotherapy

Irma C. Noordzij
1   Department of Gastroenterology and Hepatology, Catharina Hospital, Eindhoven, the Netherlands
,
Wouter L. Curvers
1   Department of Gastroenterology and Hepatology, Catharina Hospital, Eindhoven, the Netherlands
,
Clément J. Huysentruyt
2   PAMM (laboratory of Pathology and Medical Microbiology), Eindhoven, the Netherlands
,
Grard A.P. Nieuwenhuijzen
3   Department of Surgery, Catharina Hospital, Eindhoven, the Netherlands
,
Geert-Jan Creemers
4   Department of Oncology, Catharina Hospital, Eindhoven, the Netherlands
,
Maurice J.C. van der Sangen
5   Department of Radiation Oncology, Catharina Hospital, Eindhoven, the Netherlands
,
Erik J. Schoon
1   Department of Gastroenterology and Hepatology, Catharina Hospital, Eindhoven, the Netherlands
› Author Affiliations
Further Information

Publication History

submitted 19 September 2017

accepted after revision 02 February 2018

Publication Date:
11 September 2018 (online)

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Abstract

Background and study aims For early esophageal adenocarcinoma, endoscopic resection is an accepted curative treatment with an excellent long-term prognosis. Case series from Japan have reported endoscopic resection of residual esophageal squamous cell carcinoma after chemoradiotherapy. This is the first report describing endoscopic resection of residual esophageal adenocarcinoma after chemoradiotherapy. Two patients with advanced esophageal adenocarcinoma had been treated with chemoradiotherapy because comorbidity precluded esophageal resection. When residual tumor was observed endoscopically, complete remission was achieved by salvage endoscopic therapy alone or in combination with argon plasma coagulation (APC). Both patients achieved long-term sustained remission and died of non-tumor-related causes.

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