CC BY-NC-ND 4.0 · Endosc Int Open 2019; 07(11): E1448-E1454
DOI: 10.1055/a-0982-2904
Original article
Owner and Copyright © Georg Thieme Verlag KG 2019

Additional value of linked color imaging in colonoscopy: a retrospective study

Taku Sakamoto
1   Endoscopy Division, National Cancer Center Hospital, Tokyo, Japan
,
Yutaka Tomizawa
1   Endoscopy Division, National Cancer Center Hospital, Tokyo, Japan
2   Gastroenterology, Harborview Medical Center, Seattle, Washington, United States
,
Hourin Cho
1   Endoscopy Division, National Cancer Center Hospital, Tokyo, Japan
,
Hiroyuki Takamaru
1   Endoscopy Division, National Cancer Center Hospital, Tokyo, Japan
,
Masau Sekiguchi
1   Endoscopy Division, National Cancer Center Hospital, Tokyo, Japan
,
Masayoshi Yamada
1   Endoscopy Division, National Cancer Center Hospital, Tokyo, Japan
3   Division of Molecular Modification and Cancer Biology, National Cancer Center Research Institute, Tokyo, Japan
,
Takahisa Matsuda
1   Endoscopy Division, National Cancer Center Hospital, Tokyo, Japan
,
Yoshitaka Murakami
4   Department of Medical Statistics, Toho University, Tokyo, Japan
,
Yutaka Saito
1   Endoscopy Division, National Cancer Center Hospital, Tokyo, Japan
› Author Affiliations
Further Information

Publication History

submitted 18 February 2019

accepted after revision 25 June 2019

Publication Date:
22 October 2019 (online)

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Abstract

Background and study aims Linked color imaging (LCI), a newly developed optical modality, enhances mucosal surface contrast. We aimed to evaluate the efficacy and feasibility of insertion-phase LCI in terms of additional benefit of colorectal polyp detection over that obtained with white light imaging (WLI).

Patients and methods We consecutively enrolled eligible patients from November 2017 to June 2018. During colonoscopy, LCI or WLI was alternatively applied on scope insertion and LCI was applied on scope withdrawal. Patients were divided into two groups according to the protocolized difference of imaging modality used in the scope insertion phase (LCI and WLI groups). Group differences in clinical outcomes were evaluated.

Results A total of 138 patients were enrolled in this study, with equal numbers of patients assigned to the LCI and WLI groups. Most of the lesions located in the proximal colon were detected during the withdrawal phase, without a difference in proportions between the two groups. However, in the LCI group, eight of 49 lesions (16 %) located in the sigmoid and rectosigmoid colon were only detected during the insertion phase, and no such lesions (0 %) were detected during the insertion phase in the WLI group (P = 0.045).

Conclusions This study showed the efficacy and feasibility of LCI in improving colorectal polyp detection in the sigmoid colon, especially during insertion. Further studies are warranted to validate the results of our single-center study.