The band and slough technique is effective for management of diminutive type 1 gastric and duodenal neuroendocrine tumors

Fadi Hawa; Zeyad Sako; Than Nguyen; Andrew T. Catanzaro; Eugene Zolotarevsky; Angela N. Bartley; Naresh T. Gunaratnam

doi:10.1055/a-1119-6698

Endoscopy International Open, Table of Contents

CC BY-NC-ND 4.0 · Endosc Int Open 2020; 08(06): E717-E721
DOI: 10.1055/a-1119-6698

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The band and slough technique is effective for management of diminutive type 1 gastric and duodenal neuroendocrine tumors

Fadi Hawa

¹Department of Internal Medicine, St. Joseph Mercy Ann Arbor Hospital, Ypsilanti, Michigan, United States

,

Zeyad Sako

²Department of Hematology and Oncology, Ascension St. John Hospital, Detroit, Michigan, United States

,

Than Nguyen

⁴Department of Gastroenterology and Hepatology, Kaiser Permanente Vacaville Medical Center, Vacaville, California, United States

,

Andrew T. Catanzaro

³Department of Gastroenterology and Hepatology, Huron Gastroenterology Associates, St. Joseph Mercy Ann Arbor Hospital, Ypsilanti, Michigan, United States

,

Eugene Zolotarevsky

⁵Department of Gastroenterology and Hepatology, Spectrum Health Hospitals, Grand Rapids, Michigan, United States

,

Angela N. Bartley

⁶Department of Pathology, St. Joseph Mercy Ann Arbor Hospital, Ypsilanti, Michigan, United States

,

Naresh T. Gunaratnam

³Department of Gastroenterology and Hepatology, Huron Gastroenterology Associates, St. Joseph Mercy Ann Arbor Hospital, Ypsilanti, Michigan, United States

› Author Affiliations

Abstract

Background and study aims Endoscopic resection is recommended as initial treatment for early-stage gastric and duodenal neuroendocrine tumors (G-NETs and D-NETs). However, it can cause serious adverse events. We aimed to evaluate the efficacy and safety of the band and slough (BAS) technique as a novel and less aggressive endoscopic therapy for management of such tumors.

Four patients, three diagnosed with < 10-mm D-NET and one with 10-mm type I G-NET, were treated with the BAS technique without endoscopic resection. Initial follow-up endoscopy at 3 months was done to assess for residual tumor. Subsequent endoscopic surveillance was performed. After one session of banding, all patients achieved complete remission at 3-month follow-up. No tumor recurrence was detected on repeat biopsy at 12-month surveillance endoscopy. None of the patients developed any adverse events including bleeding or perforation.

The BAS technique may prove to be a safe and effective endoscopic therapy for diminutive, non-metastatic type 1 G-NETs and D-NETs. Studies of larger scale and longer follow-up periods are needed to corroborate these findings.

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References

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