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CC BY-NC-ND 4.0 · Endosc Int Open 2020; 08(05): E607-E610
DOI: 10.1055/a-1127-2991
Innovation forum

First-in-man feasibility study of a novel ingestible magnetically inflated balloon capsule for treatment of obesity

Hung Leng Kaan
1   Department of General Surgery, National University Hospital, Singapore
,
Phuoc Thien Phan
2   School of Mechanical & Aerospace Engineering, Nanyang Technological University, Singapore
,
Anthony Meng Huat Tiong
2   School of Mechanical & Aerospace Engineering, Nanyang Technological University, Singapore
,
Muneaki Miyasaka
2   School of Mechanical & Aerospace Engineering, Nanyang Technological University, Singapore
,
Soo Jay Phee
2   School of Mechanical & Aerospace Engineering, Nanyang Technological University, Singapore
,
Khek Yu Ho
3   Department of Medicine, National University of Singapore
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Abstract

Intragastric balloons (IGBs) are an established treatment option for obesity. Major barriers to dissemination of IGBs include lack of long-term efficacy outcomes, safety concerns, cost, and tolerability. We developed a novel ingestible magnetically inflated balloon capsule (IMI-BC) in hopes of overcoming these challenges. The IMI-BC is significantly cheaper than IGBs currently available on the market. We performed proof-of-concept animal studies and a first-in-human feasibility study to demonstrate the feasibility of inflating the IMI-BC using an external magnet. Further studies are currently being conducted to evaluate the safety, tolerability, and long-term efficacy of the IMI-BC. When fully developed, we anticipate that this device will benefit obese patients.



Publikationsverlauf

Eingereicht: 19. Juni 2019

Angenommen: 30. Dezember 2019

Artikel online veröffentlicht:
17. April 2020

© 2020. Owner and Copyright ©

© Georg Thieme Verlag KG
Stuttgart · New York

Kommentar zu diesem Artikel:

Endoscopy International Open – recently publishedEndoscopy 2020; 52(06): 523-523
DOI: 10.1055/a-1121-0097

 

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