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CC BY-NC-ND 4.0 · Geburtshilfe Frauenheilkd 2021; 81(05): 562-573
DOI: 10.1055/a-1228-6189
GebFra Science
Review/Übersicht

Status of Sentinel Lymph Node Biopsy in Endometrial Cancer

Article in several languages: English | deutsch
Florin Andrei Taran
Klinik für Frauenheilkunde, Universitätsklinikum Freiburg, Freiburg, Germany
,
Lisa Jung
Klinik für Frauenheilkunde, Universitätsklinikum Freiburg, Freiburg, Germany
,
Julia Waldschmidt
Klinik für Frauenheilkunde, Universitätsklinikum Freiburg, Freiburg, Germany
,
Sarah Isabelle Huwer
Klinik für Frauenheilkunde, Universitätsklinikum Freiburg, Freiburg, Germany
,
Ingolf Juhasz-Böss
Klinik für Frauenheilkunde, Universitätsklinikum Freiburg, Freiburg, Germany
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Abstract

The role of lymphadenectomy in surgical staging remains one of the biggest controversies in the management of endometrial cancer. The concept of sentinel lymph node biopsy in endometrial cancer has been evaluated for a number of years, with promising sensitivity rates and negative predictive values. The possibility of adequate staging while avoiding systematic lymphadenectomy leads to a significant reduction in the rate of peri- and postoperative morbidity. Nevertheless, the status of sentinel lymph node biopsy in endometrial cancer has not yet been fully elucidated and is variously assessed internationally. According to current European guidelines and recommendations, sentinel lymph node biopsy in endometrial cancer should be performed only in the context of clinical studies. In this review article, the developments of the past decade are explored concisely. In addition, current data regarding the technical aspects, accuracy and prognostic relevance of sentinel lymph node biopsy are explained and evaluated critically.

Key words

endometrial cancer - sentinel lymph node - sentinel mapping - ultrastaging


Publication History

Received: 27 July 2020

Accepted after revision: 01 March 2021

Article published online:
20 May 2021

© 2021. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

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