1
Department of Radiology, Medical Center – University of Freiburg, Faculty of Medicine, University of Freiburg, Germany
› Author AffiliationsSupported by:
Berta-Ottenstein-Programme for Advanced Clinician Scientists, Faculty of Medicine, University of Freiburg (Grant to P.M.J.)
Hintergrund Chondrogene Tumoren sind die häufigsten primären Knochentumoren. Maligne chondrogene Tumoren repräsentieren etwa ein Viertel der malignen Knochentumoren. Benigne chondrogene Knochentumoren sind häufige radiologische Zufallsbefunde. Radiologische Parameter können hilfreich sein zur Identifikation, Charakterisierung und Differenzialdiagnostik.
Methode Systematische Literaturrecherche mittels PubMed. Identifikation und kritische Beurteilung von Studien, welche die Bildgebung chondrogener Knochentumoren analysieren oder beschreiben.
Ergebnisse und Schlussfolgerung Nach der World-Health-Organization (WHO)-Klassifikation von 2020 werden benigne, intermediäre (lokal aggressiv oder selten metastasierend) und maligne chondrogene Tumoren unterschieden. Das typische radiologische Bild chondrogen differenzierter Tumoren ist gekennzeichnet durch ein lobuliertes Wachstumsmuster mit einem hohen Signal in T2-gewichteten Sequenzen in der Magnetresonanztomografie (MRT) und durch ein meist ring- und bogenförmiges Verkalkungsmuster in der Projektionsradiografie und der Computertomografie (CT). In Abhängigkeit der Entität ist dieses typische Muster unterschiedlich ausgeprägt. Während hochmaligne Tumoren häufig ein eindeutig malignes Wachstumsmuster zeigen, ist die Differenzierung zwischen benignen und intermediären chondrogenen Tumoren auch interdisziplinär schwierig.
Kernaussagen:
Die WHO unterscheidet gutartige, intermediäre und bösartige chondrogene Knochentumoren.
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