Die aktuelle S3-Leitlinie „Strategien zur Sicherung rationaler Antibiotika-Anwendung im Krankenhaus“ [1] fasst evidenzbasierte
Maßnahmen der Antibiotic Stewardship (ABS) zusammen, die zur Sicherung einer guten Patientenversorgung und zur Bekämpfung der mikrobiellen Resistenzentwicklung in deutschen Kliniken
beitragen sollen. Der Beitrag stellt die Leitlinie vor.
Abstract
The current S3 guideline entitled “Strategies to warrant rational in-hospital use of antibiotics” summarizes evidence-based antibiotic stewardship (ABS) measures that aim to improve
clinical outcomes and prevent development and spread of microbial resistance in German hospitals. Most important prerequisite for efficiency and safety of ABS programs is sufficient staffing
capacity as well as reliably operating surveillance of (i) pathogens, (ii) antimicrobial resistance and (iii) consumption of antimicrobials. ABS teams require authorization by hospital
institutions as units exclusively responsible for antimicrobial audits and implementation of anti-infective interventions. Clinicians should be regularly granted access to in-hospital
training programs delivered by ABS experts. Finally yet importantly, the current S3 guideline also highlights future goals, e.g., the structured involvement for nurses in ABS-guided
infection management or the promotion of ABS programs in the outpatient sector and in veterinary medicine.
Schlüsselwörter
Rationale Antibiotikaanwendung - ABS - mikrobielle Resistenz - Antibiotika - Krankenhaus
Keywords
antibiotic stewardship - microbial resistance - antibiotics - hospital